J
Jun He
Researcher at The Chinese University of Hong Kong
Publications - 17
Citations - 4588
Jun He is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 9, co-authored 11 publications receiving 4016 citations. Previous affiliations of Jun He include Zhejiang University & Beijing Institute of Genomics.
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Journal ArticleDOI
The tomato genome sequence provides insights into fleshy fruit evolution
Shusei Sato,Satoshi Tabata,Hideki Hirakawa,Erika Asamizu,Kenta Shirasawa,Sachiko Isobe,Takakazu Kaneko,Yasukazu Nakamura,Daisuke Shibata,Koh Aoki,Michael Egholm,James R. Knight,Robert Bogden,Changbao Li,Yang Shuang,Xun Xu,Shengkai Pan,Shifeng Cheng,Xin Liu,Yuanyuan Ren,Jun Wang,Alessandro Albiero,Francesca Dal Pero,Sara Todesco,Joyce Van Eck,Robert M. Buels,Aureliano Bombarely,Joseph Gosselin,Minyun Huang,Jonathan A. Leto,Naama Menda,Susan R. Strickler,Linyong Mao,Shan Gao,Isaak Y. Tecle,Thomas L. York,Yi Zheng,Julia Vrebalov,Je Min Lee,Silin Zhong,Lukas A. Mueller,Willem J. Stiekema,Paolo Ribeca,Tyler Alioto,Wencai Yang,Sanwen Huang,Yongchen Du,Zhonghua Zhang,Jianchang Gao,Yanmei Guo,Xiaoxuan Wang,Ying Li,Jun He,Chuanyou Li,Zhukuan Cheng,Jianru Zuo,Jianfeng Ren,Jiuhai Zhao,Liuhua Yan,Hongling Jiang,Bao Wang,Hongshuang Li,Zhenjun Li,Fuyou Fu,Bingtang Chen,Bin Han,Qi Feng,Danlin Fan,Ying Wang,Hong-Qing Ling,Yongbiao Xue,Doreen Ware,W. Richard McCombie,Zachary B. Lippman,Jer Ming Chia,Ke Jiang,Shiran Pasternak,Laura Gelley,Melissa Kramer,Lorinda K. Anderson,Song Bin Chang,Suzanne M. Royer,Lindsay A. Shearer,Stephen M. Stack,Jocelyn K. C. Rose,Yimin Xu,Nancy T. Eannetta,Antonio J. Matas,Ryan P. McQuinn,Steven D. Tanksley,Francisco Camara,Roderic Guigó,Stephane Rombauts,Jeffrey A. Fawcett,Yves Van de Peer,Dani Zamir,Chunbo Liang,Manuel Spannagl,Heidrun Gundlach,Rémy Bruggmann,Klaus F. X. Mayer,Zhiqi Jia,Junhong Zhang,Zhibiao Ye,Gerard J. Bishop,Sarah Butcher,Rosa Lopez-Cobollo,Daniel W. A. Buchan,Ioannis Filippis,James Abbott,Manju Singh,Alok Singh,Jitendra Kumar Pal,Awadhesh Pandit,Pradeep Kumar Singh,Ajay Kumar Mahato,Vivek Dogra,Kishor Gaikwad,Tilak Raj Sharma,Trilochan Mohapatra,Nagendra K. Singh,Mathilde Causse,Christophe Rothan,Céline Noirot,Arnaud Bellec,Christophe Klopp,Corinne Delalande,Hélène Bergès,Jérôme Mariette,Pierre Frasse,Sonia Vautrin,Toulouse Mohamed Zouine,Alain Latché,Christine Rousseau,Farid Regad,Jean-Claude Pech,Murielle Philippot,Mondher Bouzayen,Pierre Pericard,Sonia Osorio,Asuncion Fernandez Del Carmen,Antonio J. Monforte,Antonio Granell,Rafael Fernández-Muñoz,Mariana Conte,Gabriel Lichtenstein,Fernando Carrari,Gianluca De Bellis,Fabio Fuligni,Clelia Peano,Silvana Grandillo,Pasquale Termolino,Marco Pietrella,Elio Fantini,Giulia Falcone,Alessia Fiore,Giovanni Giuliano,Loredana Lopez,Paolo Facella,Gaetano Perrotta,Loretta Daddiego,Glenn J. Bryan,Biology Modesto Orozco,Xavier Pastor,David Torrents,Marco G.M. Van Schriek,Richard Feron,Jan van Oeveren,Peter De Heer,Lorena Da Ponte,Saskia Jacobs-Oomen,Mike Cariaso,Marcel Prins,Michael Josephus Theresia Van Eijk,Antoine Janssen,J. J. Van Haaren,Sung HwanJo,Jungeun Kim,Suk-Yoon Kwon,Sangmi Kim,Dal-Hoe Koo,Sanghyeob Lee,Christopher Clouser,Alain Rico,Asis Hallab,Christiane Gebhardt,Kathrin Klee,Anika Jöcker,Jens Warfsmann,Ulrike Göbel,Shingo Kawamura,Kentaro Yano,Jamie D. Sherman,Hiroyuki Fukuoka,Satomi Negoro,Sarita Bhutty,Parul Chowdhury,Debasis Chattopadhyay,Erwin Datema,Sandra Smit,Elio Schijlen,José van de Belt,Jan C. van Haarst,Sander Peters,Marjo J. van Staveren,Marleen H.C. Henkens,Paul Mooyman,Thamara Hesselink,Roeland C. H. J. van Ham,Guoyong Jiang,Marcus Droege,Doil Choi,Byung Cheol Kang,Byung-Dong Kim,Minkyu Park,Seungill Kim,Seon-In Yeom,Yong-Hwan Lee,Yang Do Choi,Guangcun Li,Jianwei Gao,Yongsheng Liu,Shengxiong Huang,Victoria Fernandez-Pedrosa,Carmen Collado,Sheila Zuñ Iga,Guoping Wang,Rebecca Cade,Robert A. Dietrich,Jane Rogers,Sandra Knapp,Zhangjun Fei,Zhangjun Fei,Ruth White,Ruth White,Theodore W. Thannhauser,Theodore W. Thannhauser,James J. Giovannoni,James J. Giovannoni,Miguel A. Botella,Louise Gilbert,Fabra Ramon Gonzalez,Jose Luis Goicoechea,Yeisoo Yu,David Kudrna,Kristi Collura,Marina Wissotski,Rod A. Wing,Blake C. Meyers,Aishwarya Bala Gurazada,Pamela J. Green,Saloni Mathur,Shailendra Vyas,Amolkumar U. Solanke,Rajesh Kumar,Vikrant Gupta,Arun Sharma,Paramjit Khurana,Jitendra P. Khurana,Akhilesh K. Tyagi,Tamas Dalmay,Irina Mohorianu,Brandon Walts,Srikar Chamala,W. Brad Barbazuk,Jingping Li,Hui Guo,Tae-Ho Lee,Yupeng Wang,Dong Zhang,Andrew H. Paterson,Xiyin Wang,Xiyin Wang,Haibao Tang,Haibao Tang,Amalia Barone,Maria Luisa Chiusano,Maria Raffaella Ercolano,Nunzio D’Agostino,Miriam Di Filippo,Alessandra Traini,Walter Sanseverino,Luigi Frusciante,Graham B. Seymour,Mounir Elharam,Ying Fu,Axin Hua,Steven Kenton,Jennifer Lewis,Shaoping Lin,Fares Z. Najar,Hongshing Lai,Baifang Qin,Ruihua Shi,Chunmei Qu,Douglas White,James R. White,Yanbo Xing,Keqin Yang,Jing Yi,Ziyun Yao,Liping Zhou,Bruce A. Roe,Alessandro Vezzi,Michela D'Angelo,Rosanna Zimbello,Riccardo Schiavon,Elisa Caniato,Chiara Rigobello,Davide Campagna,Nicola Vitulo,Giorgio Valle,David R. Nelson,Emanuele De Paoli,Dóra Szinay,Hans H. De Jong,Yuling Bai,Richard G. F. Visser,Reném Klein Lankhorst,Helen Beasley,Karen McLaren,Christine Nicholson,Claire Riddle,Giulio Gianese +323 more
TL;DR: A high-quality genome sequence of domesticated tomato is presented, a draft sequence of its closest wild relative, Solanum pimpinellifolium, is compared, and the two tomato genomes are compared to each other and to the potato genome.
Journal ArticleDOI
The genome of the cucumber, Cucumis sativus L.
Sanwen Huang,Ruiqiang Li,Zhonghua Zhang,Li Li,Xingfang Gu,Wei Fan,William J. Lucas,Xiaowu Wang,Bingyan Xie,Peixiang Ni,Yuanyuan Ren,Hongmei Zhu,Jun Li,Kui Lin,Weiwei Jin,Zhangjun Fei,Guangcun Li,Jack E. Staub,Andrzej Kilian,Edwin A. G. van der Vossen,Yang Wu,Jie Guo,Jun He,Zhiqi Jia,Yi Ren,Geng Tian,Yao Lu,Jue Ruan,Wubin Qian,Mingwei Wang,Quanfei Huang,Bo Li,Zhaoling Xuan,Jianjun Cao,Asan,Zhigang Wu,Juanbin Zhang,Qingle Cai,Yinqi Bai,Bowen Zhao,Yonghua Han,Ying Li,Xuefeng Li,Shenhao Wang,Qiuxiang Shi,Shiqiang Liu,Won Kyong Cho,Jae-Yean Kim,Yong Xu,Katarzyna Heller-Uszynska,Han Miao,Zhouchao Cheng,Shengping Zhang,Jian Wu,Yuhong Yang,Houxiang Kang,Man Li,Huiqing Liang,Xiaoli Ren,Zhongbin Shi,Ming Wen,Min Jian,Hailong Yang,Guojie Zhang,Zhentao Yang,Rui Chen,Shifang Liu,Jianwen Li,Lijia Ma,Hui Liu,Yan Zhou,Jing Zhao,Xiaodong Fang,Guoqing Li,Lin Fang,Yingrui Li,Dongyuan Liu,Hongkun Zheng,Yong Zhang,Nan Qin,Zhuo Li,Guohua Yang,Shuang Yang,Lars Bolund,Karsten Kristiansen,Hancheng Zheng,Shaochuan Li,Xiuqing Zhang,Huanming Yang,Jing Wang,Rifei Sun,Zhang Baoxi,Shuzhi Jiang,Jun Wang,Yongchen Du,Songgang Li +95 more
TL;DR: This study establishes that five of the cucumber's seven chromosomes arose from fusions of ten ancestral chromosomes after divergence from Cucumis melo, and identifies 686 gene clusters related to phloem function.
Journal ArticleDOI
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer
Jun Yu,William K.K. Wu,Xiangchun Li,Jun He,Xiaoxing Li,Simon S.M. Ng,Chang Yu,Zhibo Gao,Jie Yang,Li Miao,Qiaoxiu Wang,Qiaoyi Liang,Yi Pan,Joanna H.M. Tong,Ka F. To,Nathalie Wong,Ning Zhang,Jie Chen,Youyong Lu,Paul B.S. Lai,Francis K.L. Chan,Yingrui Li,Hsiang-Fu Kung,Huanming Yang,Jun Wang,Joseph J.Y. Sung +25 more
TL;DR: The application of next-generation sequencing has led to the identification of three novel significantly mutated genes in CRC and a mutation signature that predicts survival outcomes for stratifying patients with CRC independent of tumor-node-metastasis staging.
Journal ArticleDOI
Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing
Chang Yu,Jun Yu,Xiaotian Yao,William K.K. Wu,Youyong Lu,Senwei Tang,Xiangchun Li,Li Bao,Xiaoxing Li,Yong Hou,Renhua Wu,Min Jian,Ruoyan Chen,Fan Zhang,Lixia Xu,Fan Fan,Jun He,Qiaoyi Liang,Hongyi Wang,Xueda Hu,Minghui He,Xiang Zhang,Hancheng Zheng,Qibin Li,Hanjie Wu,Yan Chen,Xu Yang,Shida Zhu,Xun Xu,Huanming Yang,Jian Wang,Xiuqing Zhang,Joseph J.Y. Sung,Yingrui Li,Jun Wang +34 more
TL;DR: This study provides the first exome-wide evidence at single-cell level supporting that colon cancer could be of a biclonal origin, and suggests that low-prevalence mutations in a cohort may also play important protumorigenic roles at the individual level.
Journal ArticleDOI
A Snapshot of the Emerging Tomato Genome Sequence
Lukas A. Mueller,René Klein Lankhorst,Steven D. Tanksley,James J. Giovannoni,Ruth White,Julia Vrebalov,Zhangjun Fei,Joyce Van Eck,Robert M. Buels,Adri A. Mills,Naama Menda,Isaak Y. Tecle,Aureliano Bombarely,Stephen M. Stack,Suzanne M. Royer,Song Bin Chang,Lindsay A. Shearer,Byung-Dong Kim,Sung-Hwan Jo,Cheol-Goo Hur,Doil Choi,Changbao Li,Jiuhai Zhao,Hongling Jiang,Yu Geng,Yuanyuan Dai,Huajie Fan,Jinfeng Chen,Fei Lu,Jinfeng Shi,Shouhong Sun,Jianjun Chen,Xiao-Hua Yang,Chen Lu,Mingsheng Chen,Zhukuan Cheng,Chuanyou Li,Hong-Qing Ling,Yongbiao Xue,Ying Wang,Graham B. Seymour,Gerard J. Bishop,Glenn J. Bryan,Jane Rogers,Sarah Sims,Sarah Butcher,Daniel W. A. Buchan,James Abbott,Helen Beasley,Christine Nicholson,Clare Riddle,Sean Humphray,Karen McLaren,Saloni Mathur,Shailendra Vyas,Amolkumar U. Solanke,Rajesh Kumar,Vikrant Gupta,Arun Sharma,Paramjit Khurana,Jitendra P. Khurana,Akhilesh K. Tyagi,Sarita,Parul Chowdhury,Smriti Shridhar,Debasis Chattopadhyay,Awadhesh Pandit,Pradeep Kumar Singh,Ajay Kumar,Rekha Dixit,Alok Singh,Sumera Praveen,Vivek Dalal,Mahavir Yadav,Irfan Ahmad Ghazi,Kishor Gaikwad,Tilak Raj Sharma,Trilochan Mohapatra,Nagendra K. Singh,Dóra Szinay,Hans de Jong,Sander Peters,Marjo J. van Staveren,Erwin Datema,Mark Fiers,Roeland C. H. J. van Ham,P. Lindhout,Murielle Philippot,Pierre Frasse,Farid Regad,Mohamed Zouine,Mondher Bouzayen,Erika Asamizu,Shusei Sato,Hiroyuki Fukuoka,Satoshi Tabata,Daisuke Shibata,Miguel A. Botella,Manuel Pérez-Alonso,Victoria Fernandez-Pedrosa,Sonia Osorio,Amparo Mico,Antonio Granell,Zhonghua Zhang,Jun He,Sanwen Huang,Yongchen Du,Dongyu Qu,Longfei Liu,Dongyuan Liu,Jun Wang,Zhibiao Ye,Wencai Yang,Guoping Wang,Alessandro Vezzi,Sara Todesco,Giorgio Valle,Giulia Falcone,Marco Pietrella,Giovanni Giuliano,Silvana Grandillo,Alessandra Traini,Nunzio D’Agostino,Maria Luisa Chiusano,Mara Ercolano,Amalia Barone,Luigi Frusciante,Heiko Schoof,Anika Jöcker,Rémy Bruggmann,Manuel Spannagl,Klaus X.F. Mayer,Roderic Guigó,Francisco Camara,Stephane Rombauts,Jeffrey A. Fawcett,Yves Van de Peer,Sandra Knapp,Dani Zamir,Willem J. Stiekema +139 more
TL;DR: This first snapshot of the emerging tomato genome and its annotation is presented, a short comparison with potato sequence data, and the tools available for the researchers to exploit this new resource are presented.