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Institution

Marche Polytechnic University

EducationAncona, Italy
About: Marche Polytechnic University is a education organization based out in Ancona, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 5905 authors who have published 15769 publications receiving 382286 citations. The organization is also known as: Universitá Politecnica delle Marche & Universita Politecnica delle Marche.


Papers
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Journal ArticleDOI
TL;DR: A NILM algorithm based on the joint use of active and reactive power in the Additive Factorial Hidden Markov Models framework is proposed, which outperforms AFAMAP, Hart’s algorithm, and Hart's with MAP respectively.

165 citations

Journal ArticleDOI
TL;DR: The findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients, and demonstrate the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity.
Abstract: Aims The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data. Methods Cross-sectional analysis of IIM cases from 11 countries was performed. Associations between clinical subtypes, extramuscular involvement, environmental exposures and medications were investigated. Results Of 3067 IIM cases, 69% were female. The most common IIM subtype was dermatomyositis (DM) (31%). Smoking was more frequent in connective tissue disease overlap cases (45%, OR 1.44, 95% CI 1.09 to 1.90, p=0.012). Smoking was associated with interstitial lung disease (ILD) (OR 1.32, 95% CI 1.06 to 1.65, p=0.013), dysphagia (OR 1.43, 95% CI 1.16 to 1.77, p=0.001), malignancy ever (OR 1.78, 95% CI 1.36 to 2.33, p Dysphagia occurred in 39% and cardiac involvement in 9%; either occurrence was associated with higher Health Assessment Questionnaire (HAQ) scores (adjusted OR 1.79, 95% CI 1.43 to 2.23, p ILD occurred in 30%, most frequently in antisynthetase syndrome (71%, OR 10.7, 95% CI 8.6 to 13.4, p Conclusion This large multicentre cohort demonstrates the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity. Our findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients.

164 citations

Journal ArticleDOI
TL;DR: Results suggest that the probiotic has a protective action on the intestinal mucosal cells, stimulating the innate immune response after feeding for a period of six weeks, and may potentiate the immune-responsiveness of the intestine.

164 citations

Journal ArticleDOI
TL;DR: A plethora of pathological cascades triggered by gluco- and lipotoxicity are dissected, converging on candidate phenomena possibly explaining the enduring pro-inflammatory program observed in diabetic tissues, i.e. persistent immune-system stimulation, accumulation of senescent cells, epigenetic rearrangements, and alterations in microbiota composition.

163 citations

Journal ArticleDOI
TL;DR: Probiotic modulation of the gut microbiome is demonstrated, a novel gene network involved in lipid metabolism is highlighted, an insight into how the microbiome regulates molecules involved in cholesterol and triglyceride metabolism is provided, and a new potential role for L. rhamnosus is revealed in the treatment of lipid disorders.
Abstract: Lactobacillus rhamnosus lowers zebrafish lipid content by changing gut microbiota and host transcription of genes involved in lipid metabolism

163 citations


Authors

Showing all 6013 results

NameH-indexPapersCitations
Jonathan I. Epstein138112180975
Antoni Ribas13266099227
Francesco Fiori128103276699
Claudio Franceschi12085659868
Robert E. Coleman10372449796
Carmine Zoccali9981336774
Massimo Falconi9466741966
Mario Plebani91132943055
Roberto Danovaro8441523735
Rodolfo Montironi8395830957
Diego Centonze8146322857
Saverio Cinti7825632760
Michele Brignole7639926758
Jürgen P. Rabe7639120174
Jean-Jacques Body7038419608
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202376
2022181
20211,353
20201,390
20191,289
20181,148