Institution
Marche Polytechnic University
Education•Ancona, Italy•
About: Marche Polytechnic University is a education organization based out in Ancona, Italy. It is known for research contribution in the topics: Population & Cancer. The organization has 5905 authors who have published 15769 publications receiving 382286 citations. The organization is also known as: Universitá Politecnica delle Marche & Universita Politecnica delle Marche.
Topics: Population, Cancer, Medicine, Context (language use), Prostate cancer
Papers published on a yearly basis
Papers
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TL;DR: A NILM algorithm based on the joint use of active and reactive power in the Additive Factorial Hidden Markov Models framework is proposed, which outperforms AFAMAP, Hart’s algorithm, and Hart's with MAP respectively.
165 citations
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Salford Royal NHS Foundation Trust1, Manchester Academic Health Science Centre2, China-Japan Friendship Hospital3, Great Ormond Street Hospital4, Odense University Hospital5, University of Göttingen6, Pierre-and-Marie-Curie University7, Marche Polytechnic University8, University of Debrecen9, Hanoi Medical University10, University of Guadalajara11, Oslo University Hospital12, Ghent University Hospital13, University of Zurich14, University of Bath15, Royal National Hospital for Rheumatic Diseases16, University of Liverpool17, Karolinska University Hospital18, Central Manchester University Hospitals NHS Foundation Trust19
TL;DR: The findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients, and demonstrate the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity.
Abstract: Aims The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data. Methods Cross-sectional analysis of IIM cases from 11 countries was performed. Associations between clinical subtypes, extramuscular involvement, environmental exposures and medications were investigated. Results Of 3067 IIM cases, 69% were female. The most common IIM subtype was dermatomyositis (DM) (31%). Smoking was more frequent in connective tissue disease overlap cases (45%, OR 1.44, 95% CI 1.09 to 1.90, p=0.012). Smoking was associated with interstitial lung disease (ILD) (OR 1.32, 95% CI 1.06 to 1.65, p=0.013), dysphagia (OR 1.43, 95% CI 1.16 to 1.77, p=0.001), malignancy ever (OR 1.78, 95% CI 1.36 to 2.33, p Dysphagia occurred in 39% and cardiac involvement in 9%; either occurrence was associated with higher Health Assessment Questionnaire (HAQ) scores (adjusted OR 1.79, 95% CI 1.43 to 2.23, p ILD occurred in 30%, most frequently in antisynthetase syndrome (71%, OR 10.7, 95% CI 8.6 to 13.4, p Conclusion This large multicentre cohort demonstrates the importance of extramuscular involvement in patients with IIM, its association with smoking and its influence on disease severity. Our findings emphasise that IIM is a multisystem inflammatory disease and will help inform prognosis and clinical management of patients.
164 citations
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TL;DR: Results suggest that the probiotic has a protective action on the intestinal mucosal cells, stimulating the innate immune response after feeding for a period of six weeks, and may potentiate the immune-responsiveness of the intestine.
164 citations
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TL;DR: A plethora of pathological cascades triggered by gluco- and lipotoxicity are dissected, converging on candidate phenomena possibly explaining the enduring pro-inflammatory program observed in diabetic tissues, i.e. persistent immune-system stimulation, accumulation of senescent cells, epigenetic rearrangements, and alterations in microbiota composition.
163 citations
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TL;DR: Probiotic modulation of the gut microbiome is demonstrated, a novel gene network involved in lipid metabolism is highlighted, an insight into how the microbiome regulates molecules involved in cholesterol and triglyceride metabolism is provided, and a new potential role for L. rhamnosus is revealed in the treatment of lipid disorders.
Abstract: Lactobacillus rhamnosus lowers zebrafish lipid content by changing gut microbiota and host transcription of genes involved in lipid metabolism
163 citations
Authors
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Name | H-index | Papers | Citations |
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Jonathan I. Epstein | 138 | 1121 | 80975 |
Antoni Ribas | 132 | 660 | 99227 |
Francesco Fiori | 128 | 1032 | 76699 |
Claudio Franceschi | 120 | 856 | 59868 |
Robert E. Coleman | 103 | 724 | 49796 |
Carmine Zoccali | 99 | 813 | 36774 |
Massimo Falconi | 94 | 667 | 41966 |
Mario Plebani | 91 | 1329 | 43055 |
Roberto Danovaro | 84 | 415 | 23735 |
Rodolfo Montironi | 83 | 958 | 30957 |
Diego Centonze | 81 | 463 | 22857 |
Saverio Cinti | 78 | 256 | 32760 |
Michele Brignole | 76 | 399 | 26758 |
Jürgen P. Rabe | 76 | 391 | 20174 |
Jean-Jacques Body | 70 | 384 | 19608 |