Utrecht University

About: Utrecht University is a education organization based out in Utrecht, Utrecht, Netherlands. It is known for research contribution in the topics: Population & Context (language use). The organization has 58176 authors who have published 139351 publications receiving 6214282 citations. The organization is also known as: UU & Universiteit Utrecht.

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

Abstract: We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we describe EV-TRACK, a crowdsourcing knowledgebase (http://evtrack.org) that centralizes EV biology and methodology with the goal of stimulating authors, reviewers, editors and funders to put experimental guidelines into practice.

Partitioning Recent Greenland Mass Loss

Abstract: Mass budget calculations, validated with satellite gravity observations (from the Gravity Recovery and Climate Experiment (GRACE) satellites), enable us to quantify the individual components of recent Greenland mass loss. The total 2000-2008 mass loss of ~1500 gigatons, equivalent to 0.46 millimeters per year of global sea level rise, is equally split between surface processes (runoff and precipitation) and ice dynamics. Without the moderating effects of increased snowfall and refreezing, post-1996 Greenland ice sheet mass losses would have been 100% higher. Since 2006, high summer melt rates have increased Greenland ice sheet mass loss to 273 gigatons per year (0.75 millimeters per year of equivalent sea level rise). The seasonal cycle in surface mass balance fully accounts for detrended GRACE mass variations, confirming insignificant subannual variation in ice sheet discharge.

The biogenesis and functions of exosomes.

Abstract: Exosomes are membrane vesicles with a diameter of 40-100 nm that are secreted by many cell types into the extracellular milieu. They correspond to the internal vesicles of an endosomal compartment, the multivesicular body and are released upon exocytic fusion of this organelle with the plasma membrane. Intracellularly, they are formed by inward budding of the endosomal membrane in a process that sequesters particular proteins and lipids. The unique composition of exosomes may confer specific functions on them upon secretion. Although their physiological role in vivo is far from being unraveled, it is apparent that they function in a multitude of processes, including intercellular communication during the immune response. Exosomes may have evolved early in the evolution of multicellular organisms and also seem to be important for tissue developmental processes.

Levels in reflection: core reflection as a means to enhance professional growth

Abstract: Reflection is currently a key concept in teacher education. The reflection process is often described in terms of a cyclical model. In the present article, we explain how such a model can be used for supporting student teachers’ reflection on practical situations they are confronted with, and on their behaviour, skills and beliefs in such situations. In some cases, however, more fundamental issues appear to influence teachers’ practical functioning. For example, their self‐concept can have a decisive influence on the way they function, or they may do what is expected of them, and yet not feel truly involved. In such cases, a more fundamental form of reflection is needed, which in this article we refer to as ‘core reflection’. The focus on core reflection concurs with the recent emphasis in psychology on attending to people’s strengths rather than their deficiencies.