Yonsei University

About: Yonsei University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Cancer. The organization has 50162 authors who have published 106172 publications receiving 2279044 citations. The organization is also known as: Yonsei.

Recent progress in the design and applications of fluorescence probes containing crown ethers

Abstract: Crown ethers, discovered by the winner of the Nobel Prize Charles Pedersen, are cyclic chemical compounds that consist of a ring or multiple rings containing several ether groups that are capable of binding alkali ions. A smart fluorescent probe containing a crown ether moiety could be developed as a sensor for metal ions, anions and other bio-molecules and be further applied to monitor the relevant biological process in vivo. This review highlights recent advances which can be divided into seven parts: (i) fluorescent probes containing a simple crown ether or an aza-crown ether structure; (ii) fluorescent probes containing an azathia crown ether; (iii) fluorescent probes containing a cryptand; (iv) fluorescent probes containing two or more binding sites; (v) crown ether derivatives-metal complex assisted chemosensing of bioactive species; (vi) crown ether-based chemosensors for bioactive molecular detection; and (vii) efforts to improve biological relevance.

Applications of Chitin and Its Derivatives in Biological Medicine

Abstract: Chitin and its derivatives—as a potential resource as well as multiple functional substrates—have generated attractive interest in various fields such as biomedical, pharmaceutical, food and environmental industries, since the first isolation of chitin in 1811. Moreover, chitosan and its chitooligosaccharides (COS) are degraded products of chitin through enzymatic and acidic hydrolysis processes; and COS, in particular, is well suited for potential biological application, due to the biocompatibility and nontoxic nature of chitosan. In this review, we investigate the current bioactivities of chitin derivatives, which are all correlated with their biomedical properties. Several new and cutting edge insights here may provide a molecular basis for the mechanism of chitin, and hence may aid its use for medical and pharmaceutical applications.

Artificial gorilla troops optimizer: A new nature-inspired metaheuristic algorithm for global optimization problems

Abstract: Metaheuristics play a critical role in solving optimization problems, and most of them have been inspired by the collective intelligence of natural organisms in nature. This paper proposes a new metaheuristic algorithm inspired by gorilla troops' social intelligence in nature, called Artificial Gorilla Troops Optimizer (GTO). In this algorithm, gorillas' collective life is mathematically formulated, and new mechanisms are designed to perform exploration and exploitation. To evaluate the GTO, we apply it to 52 standard benchmark functions and seven engineering problems. Friedman's test and Wilcoxon rank-sum statistical tests statistically compared the proposed method with several existing metaheuristics. The results demonstrate that the GTO performs better than comparative algorithms on most benchmark functions, particularly on high-dimensional problems. The results demonstrate that the GTO can provide superior results compared with other metaheuristics.

Synthesis of silver nanoparticles using the polyol process and the influence of precursor injection.

Abstract: Spherical silver nanoparticles with various sizes and standard deviations were synthesized by the polyol process Two different synthesis methods were compared in order to investigate the influence of reaction parameters on the resulting particle size and its distribution In the precursor heating method, wherein a solution containing silver nitrate was heated to the reaction temperature, the ramping rate was determined to be a critical parameter affecting the particle size In contrast, in the precursor injection method, in which a silver nitrate aqueous solution was injected into hot ethylene glycol, because of rapid nucleation, the injection rate and the reaction temperature were important factors in terms of reducing the particle size and attaining monodispersity Silver nanoparticles with a size of 17 ? 2?nm were obtained at an injection rate of 25?ml?s?1 and a reaction temperature of 100??C