Institution
Yonsei University
Education•Seoul, South Korea•
About: Yonsei University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Population & Cancer. The organization has 50162 authors who have published 106172 publications receiving 2279044 citations. The organization is also known as: Yonsei.
Topics: Population, Cancer, Medicine, Thin film, Breast cancer
Papers published on a yearly basis
Papers
More filters
••
TL;DR: A new, selective chemosensor has been developed to detect cyanide in water at micromolar concentrations and the selectivity of the system in aqueous media for CN- over other anions is remarkably high.
270 citations
••
TL;DR: It is determined that B cell neoplasms frequently acquire methylation changes in regions already undergoing dynamic methylation during normal B cell differentiation, and this signature was particularly widespread in mature cells with an extended lifespan.
Abstract: We analyzed the DNA methylome of ten subpopulations spanning the entire B cell differentiation program by whole-genome bisulfite sequencing and high-density microarrays. We observed that non-CpG methylation disappeared upon B cell commitment, whereas CpG methylation changed extensively during B cell maturation, showing an accumulative pattern and affecting around 30% of all measured CpG sites. Early differentiation stages mainly displayed enhancer demethylation, which was associated with upregulation of key B cell transcription factors and affected multiple genes involved in B cell biology. Late differentiation stages, in contrast, showed extensive demethylation of heterochromatin and methylation gain at Polycomb-repressed areas, and genes with apparent functional impact in B cells were not affected. This signature, which has previously been linked to aging and cancer, was particularly widespread in mature cells with an extended lifespan. Comparing B cell neoplasms with their normal counterparts, we determined that they frequently acquire methylation changes in regions already undergoing dynamic methylation during normal B cell differentiation.
270 citations
••
TL;DR: In this article, a realistic approach has been made using different techniques such as compressive strength, bond strength, split tensile strength etc. Corrosion performance was evaluated using, open circuit potential measurements, rapid chloride ion permeation test and impressed voltage test and the results were discussed.
270 citations
••
TL;DR: The results indicate that PPGV could be used as an alternative measurement of HRV, and demonstrate that the parameters of PPGv are highly correlated with the parametersof HRV.
Abstract: Heart rate variability (HRV), extracted from an electrocardiogram, is known to be a noninvasive indicator reflecting the dynamic interplay between perturbations to cardiovascular function and the dynamic response of the cardiovascular regulatory system. Photoplethysmography (PPG) is a noninvasive method to monitor arterial oxygen saturation on a continuous basis. Given the rich cardiovascular information in the PPG signal, and the ubiquity and simplicity of pulse oximetry, we are investigating the feasibility of acquiring dynamics pertaining to the autonomic nervous system from PPG waveforms. To do this, we are quantifying PPG variability (PPGV). Detailed algorithmic approaches for extracting accurate PPGV signals are presented. We compare PPGV to HRV by computing time and frequency domain parameters often associated with HRV measurements, as well as approximate entropy calculations. Our results demonstrate that the parameters of PPGV are highly correlated with the parameters of HRV. Thus, our results indicate that PPGV could be used as an alternative measurement of HRV.
270 citations
••
TL;DR: Laroscopic distal gastrectomy with D2 lymphadenectomy for locally advanced gastric cancer shows benefits in terms of lower complication rate, faster recovery, and less pain compared with open surgery.
Abstract: Objective:The aim of the study was to evaluate the short-term outcomes of KLASS-02-RCT, a multicenter randomized controlled trial comparing laparoscopic distal gastrectomy (LDG) with D2 lymphadenectomy with open distal gastrectomy (ODG).Summary Background Data:Although several benefits of laparoscop
270 citations
Authors
Showing all 50632 results
Name | H-index | Papers | Citations |
---|---|---|---|
Younan Xia | 216 | 943 | 175757 |
Peer Bork | 206 | 697 | 245427 |
Ralph Weissleder | 184 | 1160 | 142508 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Gregory Y.H. Lip | 169 | 3159 | 171742 |
Yongsun Kim | 156 | 2588 | 145619 |
Jongmin Lee | 150 | 2257 | 134772 |
James M. Tiedje | 150 | 688 | 102287 |
Guanrong Chen | 141 | 1652 | 92218 |
Kazunori Kataoka | 138 | 908 | 70412 |
Herbert Y. Meltzer | 137 | 1148 | 81371 |
Peter M. Rothwell | 134 | 779 | 67382 |
Tae Jeong Kim | 132 | 1420 | 93959 |
Shih-Chang Lee | 128 | 787 | 61350 |
Ming-Hsuan Yang | 127 | 635 | 75091 |