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2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.

TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
Abstract
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...

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Real-time ultrasound elastography - a new tool for diagnosing thyroid nodules.

TL;DR: RTE is a highly sensitive and specific method of diagnosing thyroid nodules and can be employed in selecting thyroid nodule for fine-needle aspiration biopsy, according to the Ueno classification.
Journal ArticleDOI

Should small papillary thyroid cancer be observed? A population-based study.

Naris Nilubol, +1 more
- 01 Apr 2015 - 
TL;DR: The objectives of the current study were to analyze thyroid cancer-related mortality in a population‐based cohort and to determine the impact of small PTCs (defined as tumors ≤2 cm in greatest dimension) on TC‐related mortality.
Journal ArticleDOI

Overwhelming rapid metabolic and structural response to apatinib in radioiodine refractory differentiated thyroid cancer.

TL;DR: Oral apatinib seems to be a promising therapeutic option for RAIR-DTC patients and the biochemical marker (Tg) and glucose metabolism index (SUVmax) could be adopted in assessing the early response to TKI in RAIR -DTC.
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Longer-term outcomes of radiofrequency ablation for locally recurrent papillary thyroid cancer.

TL;DR: RFA seems to be an effective minimally invasive therapy for the treatment of locally recurrent PTC even in the longer-term period with mean tumor VRR of 99.5% and the complete disappearance of the treated tumors in 91.3%.
Journal ArticleDOI

Management of Differentiated Thyroid Cancer with Rising Thyroglobulin and Negative Diagnostic Radioiodine Whole Body Scan

TL;DR: A decrease in serum Tg in 62% of patients with DTC with elevated Tg and negative scan results suggests that (131)I therapy has a therapeutic effect for more than one-half of patients when the Tg level is considered an index of tumour burden.
References
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Decision aids for people facing health treatment or screening decisions

TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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