2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules: a complementary approach.
TL;DR: A complementary approach to thyroid biopsy that has worked well is described, which concomitantly uses thin, 22/20‐gauge core needle biopsy crush preparations (CP) for unsatisfactory/suboptimal FNAs.
Journal ArticleDOI
Benign call rate and molecular test result distribution of ThyroSeq v3.
N. Paul Ohori,Michael S. Landau,Sally E. Carty,Linwah Yip,Shane O. LeBeau,Pooja Manroa,Raja R. Seethala,Karen E. Schoedel,Marina N. Nikiforova,Yuri E. Nikiforov +9 more
TL;DR: The benign call rate (BCR) is the percentage of cytomorphologically indeterminate cases with subsequent benign or negative molecular results and the overall molecular result distribution of ThyroSeq v3 is evaluated.
Journal ArticleDOI
In Japanese patients with papillary thyroid carcinoma, TERT promoter mutation is associated with poor prognosis, in contrast to BRAF V600E mutation
Almira Nasirden,Tsuyoshi Saito,Yuki Fukumura,Kieko Hara,Keisuke Akaike,Aiko Kurisaki-Arakawa,Miki Asahina,Atsushi Yamashita,Ran Tomomasa,Takuo Hayashi,Atsushi Arakawa,Takashi Yao +11 more
TL;DR: In PTCs, telomerase activation by TERT promoter mutation might be more important than alternative lengthening of telomere maintenance by immunohistochemical staining for ATRX and DAXX.
Journal ArticleDOI
Surgeon volume and adequacy of thyroidectomy for differentiated thyroid cancer.
Cameron D. Adkisson,Gina M. Howell,Kelly L. McCoy,Michaele J. Armstrong,Meghan L. Kelley,Michael T. Stang,Judith M. Joyce,Steven P. Hodak,Sally E. Carty,Linwah Yip +9 more
TL;DR: Surgeons who perform ≥ 30 Tx a year are more likely to undertake the appropriate initial operation and have more complete initial resection for DTC patients, and even higher thresholds (≥ 50 Tx/year) may be necessary for patients with advanced disease.
Journal ArticleDOI
Automated thyroid nodule detection from ultrasound imaging using deep convolutional neural networks.
Fatemeh Abdolali,Jeevesh Kapur,Jacob L. Jaremko,Michelle Noga,Abhilash Rakkunedeth Hareendranathan,Kumaradevan Punithakumar +5 more
TL;DR: A novel deep neural network architecture with carefully designed loss function regularization, and network hyperparameters to perform nodule detection without complex post-processing refinement steps is proposed to outperforms the prior state-of-the-art detection methods in thyroid nodules.
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Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
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TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
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Decision aids for people facing health treatment or screening decisions
Dawn Stacey,Dawn Stacey,Krystina B. Lewis,Michael J. Barry,Carol Bennett,Karen Eden,Margaret Holmes-Rovner,Hilary A. Llewellyn-Thomas,Anne Lyddiatt,Richard Thomson,Lyndal Trevena +10 more
TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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