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Open AccessJournal ArticleDOI

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.

TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
Abstract
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...

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Pediatric Thyroid Cancer Incidence and Mortality Trends in the United States, 1973-2013.

TL;DR: The findings suggest that there may be a co-occurring increase in thyroid cancer in the pediatric population in addition to enhanced detection.
Journal ArticleDOI

Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization.

TL;DR: TERT protein was found to be more expressed in neoplastic than in normal tissues, and to display a different cellular localization, suggesting that it could contribute to thyroid cancer progression by mechanisms taking place in the cytoplasm.
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The impact of atypia/follicular lesion of undetermined significance on the rate of malignancy in thyroid fine-needle aspiration: evaluation of the Bethesda System for Reporting Thyroid Cytopathology.

TL;DR: The new AUS/FLUS category was used more often than recommended with a higher than expected rate of malignancy (20%) and Rigorous cytopathology to histopathology correlation is needed to accurately reflect the malignancies rates of the different BSRTC categories at each individual institution.
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Safety of radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: a systematic review and meta-analysis.

TL;DR: RFA was found to be safe for the treatment of benign thyroid nodules and recurrent thyroid cancers and on subgroup analysis, the overall and major complication rates were significantly higher for malignant thyroid nodule than for benign thyroid nodsules.
Journal ArticleDOI

Targeted radionuclide therapy.

TL;DR: The current status of targeted radiotherapy is reviewed as well as the advantages and disadvantages of radionuclides used for this purpose are outlined.
References
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Journal ArticleDOI

Decision aids for people facing health treatment or screening decisions

TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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