2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Thyroid Nodules with Indeterminate Cytology: Utility of the American Thyroid Association Sonographic Patterns for Cancer Risk Stratification.
Pablo Valderrabano,Melissa J. McGettigan,Cesar A. Lam,Laila Khazai,Zachary J. Thompson,Christine H. Chung,Barbara A. Centeno,Bryan McIver +7 more
TL;DR: ATA sonographic patterns are associated with distinct clinical features and pathological outcomes, and effectively stratify the cancer risk in ITNs, and should be used not only to set the size threshold for biopsy, but also to personalize management after the biopsy.
Journal ArticleDOI
Nutritional and Environmental Factors in Thyroid Carcinogenesis.
TL;DR: This review examined the other environmental carcinogens that play a role in TC, such as eating habits, living in volcanic areas, and xenobiotic elements, to better understand the mechanisms of action.
Journal ArticleDOI
Papillary thyroid carcinoma of the isthmus: Total thyroidectomy or isthmusectomy?
Ioannis Vasileiadis,Georgios Boutzios,Maria Karalaki,Evangelos P. Misiakos,Theodore Karatzas +4 more
TL;DR: Most reports support that papillary thyroid carcinomas originating in the isthmus are more likely to have multiple foci, invasion of thyroid capsule and adjacent tissues with increased rate of central node involvement, compared to carcinomas located in other parts of the thyroid.
Journal ArticleDOI
Validation of American Thyroid Association Ultrasound Risk Assessment of Thyroid Nodules Selected for Ultrasound Fine-Needle Aspiration.
TL;DR: Nodule size was inversely correlated with sonographic risk assessment, as lower risk nodules were larger on average, and Malignancy rates determined by cytology/surgical pathology were high 100%, intermediate 11%, low 8%, and very low 2%, which were closely aligned with ATA malignancy risk.
Journal ArticleDOI
Safety and tolerability of sorafenib in patients with radioiodine-refractory thyroid cancer
Francis P. Worden,Martin Fassnacht,Yuankai Shi,Tatiana Hadjieva,Françoise Bonichon,Ming Gao,Laura Fugazzola,Yuichi Ando,Yasuhisa Hasegawa,Do Joon Park,Young Kee Shong,Johannes W. A. Smit,John Chung,Christian Kappeler,Gerold Meinhardt,Martin Schlumberger,Marcia S. Brose +16 more
TL;DR: By-treatment-cycle analyses of the incidence, prevalence, and severity of hand–foot skin reaction, rash/desquamation, hypertension, diarrhea, fatigue, weight loss, increased serum thyroid stimulating hormone, and hypocalcemia are described, as well as the interventions used to manage these AEs.
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Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
David S. Cooper,Gerard M. Doherty,Bryan R. Haugen,Richard T. Kloos,Stephanie L. Lee,Susan J. Mandel,Ernest L. Mazzaferri,Bryan McIver,Furio Pacini,Martin Schlumberger,Steven I. Sherman,David L. Steward,R. Michael Tuttle +12 more
TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
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TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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