2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Maternal bisphenol A alters fetal endocrine system: Thyroid adipokine dysfunction.
TL;DR: The depraved effects of both treated groups were associated with reduced maternal and fetal body weight compared to the control group, suggesting BPA might penetrate the placental barrier and perturb the fetal thyroid adipokine axis to influence fat metabolism and the endocrine system.
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Patient age-associated mortality risk is differentiated by BRAF V600E status in papillary thyroid cancer
Xiaopei Shen,Guangwu Zhu,Rengyun Liu,David Viola,Rossella Elisei,Efisio Puxeddu,Laura Fugazzola,Carla Colombo,Barbara Jarzab,Agnieszka Czarniecka,Alfred King-Yin Lam,Caterina Mian,Federica Vianello,Linwah Yip,Garcilaso Riesco-Eizaguirre,Garcilaso Riesco-Eizaguirre,Garcilaso Riesco-Eizaguirre,Pilar Santisteban,Pilar Santisteban,Christine J. O’Neill,Mark Sywak,Roderick J. Clifton-Bligh,Bela Bendlova,Vlasta Sýkorová,Mingzhao Xing +24 more
TL;DR: The results question the conventional general use of patient age as a high-risk factor in PTC and call for differentiation between patients with BRAF V600E and wild-type BRAF when applying age to risk stratification and management of PTC.
Journal ArticleDOI
Thyroid nodules: diagnosis and management
TL;DR: Thyroid ultrasonography should be performed only for palpable goitre and thyroid nodules and by specialists with expertise in thyroid sonography, and surgery is indicated for FNA findings of malignancy or indeterminate cytology when there is a high risk clinical context.
Journal ArticleDOI
Comparison among TIRADS (ACR TI-RADS and KWAK- TI-RADS) and 2015 ATA Guidelines in the diagnostic efficiency of thyroid nodules.
Luying Gao,Xuehua Xi,Yuxin Jiang,Xiao Yang,Ying Wang,Shenling Zhu,Xingjian Lai,Xiaoyan Zhang,Ruina Zhao,Bo Zhang +9 more
TL;DR: The TIRADS (KWAK-TIRADS and ACR TI-RADS) category and ATA guidelines perform better in differentiating nodules >1 cm than nodule ≤1 cm than other methods.
Journal ArticleDOI
Ultrasonography scoring systems can rule out malignancy in cytologically indeterminate thyroid nodules.
Giorgio Grani,Livia Lamartina,Valeria Ascoli,Daniela Bosco,Francesco Nardi,Ferdinando D'Ambrosio,Antonello Rubini,Laura Giacomelli,Marco Biffoni,Sebastiano Filetti,Cosimo Durante,Vito Cantisani +11 more
TL;DR: With stringent negativity cut-offs, American Thyroid Association and Thyroid Imaging Reporting and Data System assessment of cytologically indeterminate thyroid nodules allows high-confidence exclusion of malignancy.
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TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
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Decision aids for people facing health treatment or screening decisions
Dawn Stacey,Dawn Stacey,Krystina B. Lewis,Michael J. Barry,Carol Bennett,Karen Eden,Margaret Holmes-Rovner,Hilary A. Llewellyn-Thomas,Anne Lyddiatt,Richard Thomson,Lyndal Trevena +10 more
TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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