2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Long-term efficacy of lymph node reoperation for persistent papillary thyroid cancer.
Osama Al-Saif,William B. Farrar,Mark Bloomston,Kyle Porter,Matthew D. Ringel,Richard T. Kloos +5 more
TL;DR: Surgical resection of persistent PTC in cervical lymph nodes achieves BCR, when most stringently defined, in 27% of patients, sometimes requiring several surgeries, no biochemical or clinical recurrences occurred during follow-up.
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Insights into the Management of Papillary Microcarcinoma of the Thyroid.
TL;DR: Interestingly, older patients with low-risk PMCs are the best candidates for active surveillance, and they are most unlikely to grow in older patients (≥60 years).
Journal ArticleDOI
The association between serum TSH concentration and thyroid cancer
TL;DR: Analysis of the relationship between serum TSH and diagnosis of papillary thyroid cancer in 10 178 patients with nodular thyroid disease who were investigated by fine-needle aspiration biopsy found significantly higher TSH concentrations in patients who were subsequently diagnosed with thyroid cancer compared with those with benign disease.
Journal ArticleDOI
Increasing incidence of thyroid cancer: controversies explored
TL;DR: Nature Reviews Endocrinology asks four experts their opinions on some of the controversies surrounding the changing trends in thyroid cancer incidence.
Journal ArticleDOI
Male sex, single nodularity, and young age are associated with the risk of finding a papillary thyroid cancer on fine-needle aspiration cytology in a large series of patients with nodular thyroid disease
Teresa Rago,Emilio Fiore,M Scutari,Ferruccio Santini,G. Di Coscio,R Romani,Paolo Piaggi,Clara Ugolini,Fulvio Basolo,Paolo Miccoli,Aldo Pinchera,P Vitti +11 more
TL;DR: A cytology suspicious or indicative of PTC was associated with younger age, male gender, and solitary versus multiple nodularity, together with serum TSH, which may allow formulation of an algorithm that could be usefully applied to predict the risk of P TC in individual patients when cytology does not give a diagnostic result.
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Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
David S. Cooper,Gerard M. Doherty,Bryan R. Haugen,Richard T. Kloos,Stephanie L. Lee,Susan J. Mandel,Ernest L. Mazzaferri,Bryan McIver,Furio Pacini,Martin Schlumberger,Steven I. Sherman,David L. Steward,R. Michael Tuttle +12 more
TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
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TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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