2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Measurement and Variation in Estimation of Quality of Life Effects of Patients Undergoing Treatment for Papillary Thyroid Carcinoma
Carrie C. Lubitz,Lucia De Gregorio,Abbey L. Fingeret,Konstantinos P. Economopoulos,Diana Termezawi,Mursal Hassan,Sareh Parangi,Antonia E. Stephen,Elkan F. Halpern,Karen Donelan,J. Shannon Swan +10 more
TL;DR: The results support the measurement of a similar underlying construct, although variation in detecting changes in health exists between the instruments, and the SF6D is the most responsive to treatment effects and should be utilized in future economic analyses in this patient population.
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Differential Diagnosis of Benign and Malignant Thyroid Nodules Using Deep Learning Radiomics of Thyroid Ultrasound Images
TL;DR: DLRT shows the best overall performance comparing with other deep learning models and human observers and holds great promise for improving the differential diagnosis of benign and malignant thyroid nodules.
Journal ArticleDOI
Cost-effectiveness of lobectomy versus genetic testing (Afirma®) for indeterminate thyroid nodules: Considering the costs of surveillance.
TL;DR: The base case estimate suggests that diagnostic lobectomy dominates genetic testing as a strategy for ruling out malignancy of indeterminate thyroid nodules, and these results, however, were highly sensitive to estimates of utilities after lobectomy and living under surveillance after Afirma®.
Journal ArticleDOI
Insulin Resistance: Any Role in the Changing Epidemiology of Thyroid Cancer?
TL;DR: This review summarizes the current literature evaluating the relationship between metabolic disorders characterized by insulin resistance and the risk for TC as well as the possible underlying mechanisms.
Journal ArticleDOI
Effect of Tumor Size and Minimal Extrathyroidal Extension in Patients with Differentiated Thyroid Cancer.
Samantha Tam,Moran Amit,Mongkol Boonsripitayanon,Naifa L. Busaidy,Maria E. Cabanillas,Steven G. Waguespack,Neil D. Gross,Elizabeth G. Grubbs,Michelle D. Williams,Stephen Y. Lai,Erich M. Sturgis,Mark Zafereo +11 more
TL;DR: Tumor size, but not the presence of mETE, was an independent predictor of DFS, LRF, and DMF in DTC.
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