2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R. Haugen,Erik K. Alexander,Keith C. Bible,Gerard M. Doherty,Susan J. Mandel,Yuri E. Nikiforov,Furio Pacini,Gregory W. Randolph,Anna M. Sawka,Martin Schlumberger,Kathryn G. Schuff,Steven I. Sherman,Julie Ann Sosa,David L. Steward,R. Michael Tuttle,Leonard Wartofsky +15 more
TLDR
Evidence-based recommendations are developed to inform clinical decision-making in the management of thyroid nodules and differentiated thyroid cancer and represent, in the authors' opinion, contemporary optimal care for patients with these disorders.Abstract:
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer. Methods: The specific clinical questions addressed in these guidelines were based on prior versions of the guidelines, stakeholder input, and input of task force members. Task force panel members were educated on knowledge synthesis methods, including electronic database searching, review and selection of relevant citations, and critical appraisal of selected studies. Published English language articles on adults were eligible for inclusion. The American College of Physicians Guideline Gr...read more
Citations
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Thyroid lobectomy for treatment of well differentiated intrathyroid malignancy.
Iain J. Nixon,Ian Ganly,Snehal G. Patel,Frank L. Palmer,Monica M. Whitcher,R. M. Tuttle,Ashok R. Shaha,Jatin P. Shah +7 more
TL;DR: Patients with pT1T2 N0 WDTC can be safely managed by thyroid lobectomy alone, according to previous evidence from large institutions suggesting that lobectomy provides similar excellent results.
Journal ArticleDOI
Preoperative staging of papillary thyroid carcinoma: comparison of ultrasound imaging and CT.
TL;DR: High-resolution ultrasound can be accurate in preoperative evaluation for extrathyroidal tumor extension and lateral lymph node metastasis and for papillary thyroid microcarcinoma there was no significant difference in the diagnostic accuracy rates of ultrasound, CT, and the combination of ultrasound and CT.
Journal ArticleDOI
Malignancy rate in thyroid nodules classified as bethesda category III (AUS/FLUS)
Allen S. Ho,Evan E. Sarti,Kunal S. Jain,Hangjun Wang,Iain J. Nixon,Ashok R. Shaha,Jatin P. Shah,Dennis H. Kraus,Ronald Ghossein,Stephanie Fish,Richard J. Wong,Oscar Lin,Luc G. T. Morris +12 more
TL;DR: In patients presenting to a comprehensive cancer center, malignancy rates in nodules with AUS/FLUS cytology are higher than previously estimated, with 26.6-37.8% of AUS-FLUS nodules harboring cancer.
Journal ArticleDOI
Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology: A Prospective Blinded Multicenter Study.
David L. Steward,Sally E. Carty,Rebecca S. Sippel,Samantha Peiling Yang,Julie Ann Sosa,Julie Ann Sosa,Jennifer A. Sipos,James J Figge,Susan J. Mandel,Bryan R. Haugen,Kenneth D. Burman,Zubair W. Baloch,Ricardo V. Lloyd,Raja R. Seethala,William E. Gooding,Simion I. Chiosea,Cristiane Gomes-Lima,Robert L. Ferris,Jessica M. Folek,Raheela Khawaja,Priya Kundra,Kwok Seng Loh,Carrie Marshall,Sarah E. Mayson,Kelly L. McCoy,Min En Nga,Kee Yuan Ngiam,Marina N. Nikiforova,Jennifer L. Poehls,Matthew D. Ringel,Huaitao Yang,Linwah Yip,Yuri E. Nikiforov +32 more
TL;DR: In this prospective, blinded, multicenter study, the multigene GC test demonstrated a high sensitivity/NPV and reasonably high specificity/PPV, which may obviate diagnostic surgery in up to 61% of patients with Bethesda III to IV indeterminate nodules, and up to 82% of all benign nodules with indeterminates cytology.
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2013 European Thyroid Association Guidelines for Cervical Ultrasound Scan and Ultrasound-Guided Techniques in the Postoperative Management of Patients with Thyroid Cancer
TL;DR: Standardization of the US scanning procedure, techniques of US-guided fine-needle aspiration, and reporting of findings are presented, and definition of criteria for classification of malignancy risk based on cervical US imaging characteristics of neck masses and lymph nodes are presented.
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TL;DR: Evidence-based recommendations in response to the appointment as an independent task force by the American Thyroid Association to assist in the clinical management of patients with thyroid nodules and differentiated thyroid cancer represent, in the authors' opinion, contemporary optimal care for patients with these disorders.
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TL;DR: Decision aids reduced the proportion of undecided participants and appeared to have a positive effect on patient-clinician communication, and those exposed to a decision aid were either equally or more satisfied with their decision, the decision-making process, and the preparation for decision making compared to usual care.
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