Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
Benjamin T. Bradley,Heather Maioli,Robert Johnston,Irfan Chaudhry,Susan L. Fink,Haodong Xu,Behzad Najafian,Gail H. Deutsch,J Matthew Lacy,Timothy L. Williams,Nicole A. Yarid,Desiree A. Marshall +11 more
TLDR
In this paper, the authors provide a clinicopathological report of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases by documenting histopathological changes and evidence of SARS CoV2 tissue tropism.About:
This article is published in The Lancet.The article was published on 2020-08-01 and is currently open access. It has received 587 citations till now. The article focuses on the topics: Diffuse alveolar damage & Kidney disease.read more
Citations
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Review of cardiopulmonary autopsy findings in deceased covid-19 positive patients in a tertiary care center in central india
Ganguly S,Barpande Cp,Singh Bp +2 more
TL;DR: The present study aims to document the cardiopulmonary abnormalities found in autopsies of COVID-positive patients conducted at the institution while simultaneously conducting a review of the available international literature on the related topic.
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Postmortem Histopathologic Findings and SARS-CoV-2 Detection in Autopsy Kidneys of Patients With COVID-19: A Systematic Review and Meta-Analysis.
Mahsa Mahjani,Mahmoud Parvin,Saeed Ghobadi,Alireza Jafari,Hassan Ahangar,S. Gohari,Sepehr Gohari +6 more
TL;DR: A systematic review and meta-analysis aimed to investigate the prevalence of postmortem kidney histopathologic features of patients with COVID-19 in addition to the rate of renal tropism in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as discussed by the authors .
Journal ArticleDOI
Increasing rate of hospitalization for severe peptic ulcer in digestive disease emergencies after the pandemic
TL;DR: Wang et al. as discussed by the authors evaluated the incidence of each major type of digestive disease before and after the pandemic in adults at the 2 hospitals, which experienced coronavirus disease 2019 outbreaks with varying severity.
Journal ArticleDOI
Viruses and Endocrine Diseases
Magloire Pandoua Nekoua,Cyril Debuysschere,Inès Vergez,Corentin Morvan,Chaldam Jespère Mbani,Famara Sane,Enagnon Kazali Alidjinou,Didier Hober +7 more
TL;DR: A review of the impact of viral infections on the human endocrine system is provided in this article , in order to provide new avenues for the control of endocrine diseases, such as cancer.
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Dysregulated platelet function in COVID-19 patients
N. R. Gashimova,Viktoriya Bitsadze,L.L. Pankratyeva,Jamilya Khizroeva,E. V. Slukhanchuk,K. N. Grigoreva,V. I. Tsibizova,J.-Ch. Gris,Ismail Elalamy,C. Ay,D. V. Blinov,Vladimir Serov,A. D. Makatsariya +12 more
TL;DR: A role of platelets in the pathogenesis of COVID-19 has not been examined in this article , however, the authors have shown that platelet dysfunction includes both thrombocytopenia and platelet hyperactivation.
References
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A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann,Hannah Kleine-Weber,Simon Schroeder,Nadine Krüger,Tanja Herrler,Sandra Erichsen,Tobias S. Schiergens,Georg Herrler,Nai Huei Wu,Andreas Nitsche,Marcel A. Müller,Christian Drosten,Christian Drosten,Stefan Pöhlmann +13 more
TL;DR: It is demonstrated that SARS-CoV-2 uses the SARS -CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming, and it is shown that the sera from convalescent SARS patients cross-neutralized Sars-2-S-driven entry.
Journal ArticleDOI
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
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Pathological findings of COVID-19 associated with acute respiratory distress syndrome.
Zhe Xu,Lei Shi,Yijin Wang,Ji-Yuan Zhang,Lei Huang,Chao Zhang,Shuhong Liu,Peng Zhao,Hongxia Liu,Li Zhu,Yanhong Tai,Changqing Bai,Tingting Gao,Jin-Wen Song,Peng Xia,Jing-Hui Dong,Jingmin Zhao,Fu-Sheng Wang +17 more
TL;DR: O surto do novo coronavÃrus (COVID-19) em Wuhan, China, iniciado em dezembro de 2019, evoluiu para se tornar uma pandemia global A.
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