Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
Benjamin T. Bradley,Heather Maioli,Robert Johnston,Irfan Chaudhry,Susan L. Fink,Haodong Xu,Behzad Najafian,Gail H. Deutsch,J Matthew Lacy,Timothy L. Williams,Nicole A. Yarid,Desiree A. Marshall +11 more
TLDR
In this paper, the authors provide a clinicopathological report of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases by documenting histopathological changes and evidence of SARS CoV2 tissue tropism.About:
This article is published in The Lancet.The article was published on 2020-08-01 and is currently open access. It has received 587 citations till now. The article focuses on the topics: Diffuse alveolar damage & Kidney disease.read more
Citations
More filters
Journal ArticleDOI
SARS-CoV-2 tracheitis in laryngectomized patients: a consecutive case-series study
Ignacio Javier Fernandez,Federico Spagnolo,Sara Valerini,Francesco Mattioli,Gabriele Molteni,Alessandro Marchioni,Daniela Lucidi +6 more
TL;DR: SARS-CoV-2 is a possible cause of acute severe tracheitis in laryngectomees and the present cases highlight the need for close interdisciplinary working and communication in the management of airway complications of COVID-19 infection.
Journal ArticleDOI
Current topic of vascular function in hypertension
TL;DR: In this article , the authors summarized new findings on vascular function and discussed the association between vascular functions and COVID-19, the importance of lifestyle modifications for the maintenance of vascular function, and the usefulness of vascular functions tests for cardiovascular risk assessment.
Journal ArticleDOI
Direct, indirect, post-infection damages induced by coronavirus in the human body: an overview
Sivan Padma Priya,P M Sunil,Sudhir Varma,Carel Brigi,Mohammad Faruq Abd Rachman Isnadi,J A Jayalal,Rengasayee Arunkumar Shadamarshan,S. Suresh Kumar,Neela Kumari,Rishi Kumar +9 more
TL;DR: In this paper , the authors performed an electronic database search according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines with selective inclusion and exclusion criteria.
Posted ContentDOI
An iTSC-derived placental model of SARS-CoV-2 infection unveils ACE2-dependent susceptibility in syncytiotrophoblasts
Joseph Chen,Joseph Chen,Joseph Chen,Jessica A. Neil,Jia Ping Tan,Jia Ping Tan,Jia Ping Tan,Raj Rudraraju,Monika Mohenska,Monika Mohenska,Monika Mohenska,Yu By Sun,Yu By Sun,Yu By Sun,Guizhi Sun,Guizhi Sun,Guizhi Sun,Yichen Zhou,Yichen Zhou,Yichen Zhou,Ying Li,Damien R. Drew,Damien R. Drew,Phill Pymm,Phill Pymm,Wai-Hong Tham,Wai-Hong Tham,Fernando J. Rossello,Fernando J. Rossello,Guiying Nie,Xiaodong Liu,Xiaodong Liu,Xiaodong Liu,Kanta Subbarao,Jose M. Polo,Jose M. Polo,Jose M. Polo +36 more
TL;DR: In this article, the authors developed an in vitro model of SARS-CoV-2 infection of placental cell types using induced trophoblast stem cells (iTSCs).
Journal ArticleDOI
U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients.
TL;DR: In this paper, the authors found that high hemoglobin (Hb) level might be associated with hypercoagulable state and death due to COVID-19 patients.
References
More filters
Journal ArticleDOI
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann,Hannah Kleine-Weber,Simon Schroeder,Nadine Krüger,Tanja Herrler,Sandra Erichsen,Tobias S. Schiergens,Georg Herrler,Nai Huei Wu,Andreas Nitsche,Marcel A. Müller,Christian Drosten,Christian Drosten,Stefan Pöhlmann +13 more
TL;DR: It is demonstrated that SARS-CoV-2 uses the SARS -CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming, and it is shown that the sera from convalescent SARS patients cross-neutralized Sars-2-S-driven entry.
Journal ArticleDOI
Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention
Zunyou Wu,Jennifer M. McGoogan +1 more
TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
Journal ArticleDOI
Pathological findings of COVID-19 associated with acute respiratory distress syndrome.
Zhe Xu,Lei Shi,Yijin Wang,Ji-Yuan Zhang,Lei Huang,Chao Zhang,Shuhong Liu,Peng Zhao,Hongxia Liu,Li Zhu,Yanhong Tai,Changqing Bai,Tingting Gao,Jin-Wen Song,Peng Xia,Jing-Hui Dong,Jingmin Zhao,Fu-Sheng Wang +17 more
TL;DR: O surto do novo coronavÃrus (COVID-19) em Wuhan, China, iniciado em dezembro de 2019, evoluiu para se tornar uma pandemia global A.
Related Papers (5)
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more