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Impact of obesity on infertility in women.

TLDR
Overweight women have a higher incidence of menstrual dysfunction and anovulation, and are at a high risk for reproductive health, and weight loss has beneficial effects on the reproductive outcomes in patients.
Abstract
The prevalence of obesity and overweight are increasing and have become an epidemic worldwide. Obesity has detrimental influences on all systems, including reproductive health. The prevalence of obesity in infertile women is high, and it is well known that there is an association between obesity and infertility. The relationship between obesity and reproductive functions is still being explored. Overweight women have a higher incidence of menstrual dysfunction and anovulation. Overweight and obese women are at a high risk for reproductive health. The risk of subfecundity and infertility, conception rates, miscarriage rates, and pregnancy complications are increased in these women. They have poor reproductive outcomes in natural as well as assisted conception. These poor reproductive outcomes include assisted reproduction such as ovulation induction, in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), and ovum donation cycles. Weight loss has beneficial effects on the reproductive outcomes in these patients.

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Journal ArticleDOI

Obezitenin Kadın Sağlığına Etkileri

TL;DR: Maternal obezite olumsuz gebelik sonuclarina (spontan dusuk, gestasyonel diyabet, hipertansif hastaliklar) ve emzirmeye baslama ve devamin azalmasina yol acmaktadir makalede obezitenin kadin sagligina etkileri literatur dogrultusunda ozetlenmistir.
Journal ArticleDOI

The challenges of obesity for fertility: A FIGO literature review

TL;DR: In this article , a multidisciplinary approach was proposed to improve care for people living with obesity and infertility with empathy, via a multi-disciplinary approach, which can contribute to their economic and psychosocial stressors.
Journal ArticleDOI

The effect of obesity on human reproductive health and foetal life.

TL;DR: In this paper, the authors reported that an increased body mass index (BMI) may lead to low semen quality, poor sperm motility, and reduced fertilization rates in men as well as anovulation, pregnancy loss, diminished pregnancy, and low live birth rates in women.
Journal ArticleDOI

The Mechanism of Zinc Sulfate in Improving Fertility in Obese Rats Analyzed by Sperm Proteomic Analysis.

TL;DR: ZnSO4 may improve the fertility of obese male rats by regulating protein expression related to metabolism, inflammation, and sperm maturation by regulatingprotein expression related as well as improving testicular structure and spermatogenesis abnormalities caused by obesity.
References
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Journal ArticleDOI

The hormone resistin links obesity to diabetes

TL;DR: It is shown that adipocytes secrete a unique signalling molecule, which is named resistin (for resistance to insulin), which circulating resistin levels are decreased by the anti-diabetic drug rosiglitazone, and increased in diet-induced and genetic forms of obesity.
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Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

TL;DR: The pathophysiology of adiponectin and adiponECTin receptors in insulin resistance, diabetes, and the metabolic syndrome is described and potential versatile therapeutic targets to combat obesity-linked diseases characterized by insulin resistance are described.
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Adiponectin and Adiponectin Receptors

TL;DR: It is shown that AdipoR1 and AdIPoR2 serve as receptors for globular and full-length adiponectin and mediate increased AMP-activated protein kinase, peroxisome proliferator-activated receptor-alpha ligand activities, and glucose uptake and fatty-acid oxidation by adiponECTin.
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Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment.

TL;DR: Weight loss should be considered as a first option for women who are infertile and overweight, and the cost savings of the programme were considerable.
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