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Open AccessJournal ArticleDOI

Impact of obesity on infertility in women.

TLDR
Overweight women have a higher incidence of menstrual dysfunction and anovulation, and are at a high risk for reproductive health, and weight loss has beneficial effects on the reproductive outcomes in patients.
Abstract
The prevalence of obesity and overweight are increasing and have become an epidemic worldwide. Obesity has detrimental influences on all systems, including reproductive health. The prevalence of obesity in infertile women is high, and it is well known that there is an association between obesity and infertility. The relationship between obesity and reproductive functions is still being explored. Overweight women have a higher incidence of menstrual dysfunction and anovulation. Overweight and obese women are at a high risk for reproductive health. The risk of subfecundity and infertility, conception rates, miscarriage rates, and pregnancy complications are increased in these women. They have poor reproductive outcomes in natural as well as assisted conception. These poor reproductive outcomes include assisted reproduction such as ovulation induction, in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), and ovum donation cycles. Weight loss has beneficial effects on the reproductive outcomes in these patients.

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Citations
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Journal ArticleDOI

Obesity in Infertile Women, a Cross-Sectional Study of the United States Using NSFG 2011-2019.

TL;DR: In this article, the authors conducted a secondary analysis of National Survey of Family Growth (NSFG) data from 2011 to 2019 and found that obese women had 62% higher odds of infertility compared to non-obese women of reproductive age.
Book ChapterDOI

Hypothalamic Cell Models

TL;DR: The hypothalamus is a vital and an integral part of the central nervous system as it regulates a wide range of physiological and psychological processes, including energy homeostasis, reproduction, circadian rhythms, as well as emotional and behavioral patterns as mentioned in this paper.
Journal ArticleDOI

Effect of BMI on the value of serum progesterone to predict clinical pregnancy outcome in IVF/ICSI cycles: a retrospective cohort study

TL;DR: In this article , the effects of progesterone elevation on triggering day on clinical pregnancy rate (CPR) of IVF/ICSI cycles in patients with different female BMI were investigated.
Book ChapterDOI

Obesity and Medically Assisted Reproduction

TL;DR: It is not recommended that ART be withheld from women with elevated BMI, but appropriate counseling about increased risks should be given along with referrals for comprehensive weight management.
Journal ArticleDOI

Weight Status of Brazilian’s Mother-Son Dyad after Maternal Bariatric Surgery

TL;DR: Despite differences in the characteristics of public and private systems, the mother-child dyads in both groups achieved satisfactory post-bariatric surgery gestation outcomes and almost 90% of children were born at full term and with adequate weights.
References
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Journal ArticleDOI

The hormone resistin links obesity to diabetes

TL;DR: It is shown that adipocytes secrete a unique signalling molecule, which is named resistin (for resistance to insulin), which circulating resistin levels are decreased by the anti-diabetic drug rosiglitazone, and increased in diet-induced and genetic forms of obesity.
Journal ArticleDOI

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

TL;DR: The pathophysiology of adiponectin and adiponECTin receptors in insulin resistance, diabetes, and the metabolic syndrome is described and potential versatile therapeutic targets to combat obesity-linked diseases characterized by insulin resistance are described.
Journal ArticleDOI

Adiponectin and Adiponectin Receptors

TL;DR: It is shown that AdipoR1 and AdIPoR2 serve as receptors for globular and full-length adiponectin and mediate increased AMP-activated protein kinase, peroxisome proliferator-activated receptor-alpha ligand activities, and glucose uptake and fatty-acid oxidation by adiponECTin.
Journal ArticleDOI

Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment.

TL;DR: Weight loss should be considered as a first option for women who are infertile and overweight, and the cost savings of the programme were considerable.
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