Journal ArticleDOI
Iron oxide-manganese oxide nanoparticles with tunable morphology and switchable MRI contrast mode triggered by intracellular conditions.
David Garcia Soriano,Paula Milán-Rois,Nuria Lafuente-Gómez,Cristina Navío,Lucía Gutiérrez,Lorena Cussó,Manuel Desco,Daniel Calle,A. Somoza,Gorka Salas +9 more
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In this paper , the authors describe the preparation of hybrid IR-manganese oxide core-satellite shell nanostructures that change their contrast mode in magnetic resonance imaging (MRI) from T2 to T1, after being internalized by cells.About:
This article is published in Journal of Colloid and Interface Science.The article was published on 2022-01-01. It has received 4 citations till now. The article focuses on the topics: Medicine & Dissolution.read more
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Engineered Bacteria with Genetic Circuits Accumulating Nanomagnets as MRI Contrast Agents.
Merve Yavuz,Mustafa Ütkür,Ebru Şahin Kehribar,Ecrin Yagiz,Emine Ulku Saritas,Urartu Ozgur Safak Seker +5 more
TL;DR: The work demonstrates that the combinatorial effect of Mms6 with ferroxidase, iron transporter protein, and material binding peptide enhances the paramagnetic behavior of the cells in magnetic resonance imaging (MRI) measurements.
Journal ArticleDOI
Synergistic immunomodulatory effect in macrophages mediated by magnetic nanoparticles modified with miRNAs.
Nuria Lafuente-Gómez,Shiqi Wang,Flavia Fontana,Mónica Dhanjani,David Garcia Soriano,Alexandra Correia,Milagros Castellanos,Ciro Rodriguez Diaz,Gorka Salas,Hélder A. Santos,A. Somoza +10 more
TL;DR: It is proved that C MD-MNP-miRNA155 and CMD-M NP-mi RNA125b nanoparticles can display a pro-inflammatory response in human macrophages by increasing the expression of CD80 and the levels of TNF-α and IL-6.
Journal ArticleDOI
Gd(OH)3 as Modifier of Iron Oxide Nanoparticles—Insights on the Synthesis, Characterization and Stability
María Gabriela Montiel Schneider,P. S. Rivero,Guillermo Arturo Muñoz Medina,Francisco H. Sánchez,Verónica Leticia Lassalle +4 more
TL;DR: In this article , the authors presented the obtained results of the synthesis of hybrid nanoparticles composed of magnetite/maghemite and gadolinium hydroxide, which can generate both positive and negative contrast with a single administration.
Journal ArticleDOI
Theranostic Approach for the Management of Osteoporosis.
TL;DR: In this article , the authors highlight the pathophysiology of osteoporosis, conventional techniques of diagnosis, and the application of superparamagnetic iron oxide nanoparticles (SPIONs) for diagnostic and treatment purposes.
References
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Journal ArticleDOI
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.
Hyuna Sung,Jacques Ferlay,Rebecca L. Siegel,Mathieu Laversanne,Isabelle Soerjomataram,Ahmedin Jemal,Freddie Bray +6 more
TL;DR: The GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer (IARC) as mentioned in this paper show that female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung cancer, colorectal (11 4.4%), liver (8.3%), stomach (7.7%) and female breast (6.9%), and cervical cancer (5.6%) cancers.
Journal ArticleDOI
Ultra-large-scale syntheses of monodisperse nanocrystals.
Jongnam Park,Kwangjin An,Yosun Hwang,Je-Geun Park,Han-Jin Noh,Jae Young Kim,Jae-Hoon Park,Nong-Moon Hwang,Taeghwan Hyeon +8 more
TL;DR: This work is able to synthesize as much as 40 g of monodisperse nanocrystals in a single reaction, without a size-sorting process, and the particle size could be controlled simply by varying the experimental conditions.
Journal ArticleDOI
Monodisperse MFe2O4 (M = Fe, Co, Mn) Nanoparticles
Shouheng Sun,Hao Zeng,David B. Robinson,Simone Raoux,Philip M. Rice,Shan X. Wang,Guanxiong Li +6 more
TL;DR: As-synthesized iron oxide nanoparticles have a cubic spinel structure as characterized by HRTEM, SAED, and XRD and can be transformed into hydrophilic ones by adding bipolar surfactants, and aqueous nanoparticle dispersion is readily made.
Journal ArticleDOI
Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths.
TL;DR: Awareness of the field strength and solvent associated with relaxivity data is crucial for the comparison and evaluation of relaxivity values and should be replaced by relaxivities measured at 1.5 T and at 3 T in plasma at physiological temperature.
Journal ArticleDOI
Diverse Applications of Nanomedicine
Beatriz Pelaz,Christoph Alexiou,Ramon A. Alvarez-Puebla,Frauke Alves,Frauke Alves,Anne M. Andrews,Sumaira Ashraf,Lajos P. Balogh,Laura Ballerini,Alessandra Bestetti,Cornelia Brendel,Susanna Bosi,Mónica Carril,Warren C. W. Chan,Chunying Chen,Xiaodong Chen,Xiaoyuan Chen,Zhen Cheng,Daxiang Cui,Jianzhong Du,Christian Dullin,Alberto Escudero,Alberto Escudero,Neus Feliu,Mingyuan Gao,Michael D. George,Yury Gogotsi,Arnold Grünweller,Zhongwei Gu,Naomi J. Halas,Norbert Hampp,Roland K. Hartmann,Mark C. Hersam,Patrick Hunziker,Ji Jian,Xingyu Jiang,Philipp Jungebluth,Pranav Kadhiresan,Kazunori Kataoka,Ali Khademhosseini,Jindřich Kopeček,Nicholas A. Kotov,Harald F. Krug,Dong Soo Lee,Claus-Michael Lehr,Kam W. Leong,Xing-Jie Liang,Mei Ling Lim,Luis M. Liz-Marzán,Xiaowei Ma,Paolo Macchiarini,Huan Meng,Helmuth Möhwald,Paul Mulvaney,Andre E. Nel,Shuming Nie,Peter Nordlander,Teruo Okano,Jose Oliveira,Tai Hyun Park,Reginald M. Penner,Maurizio Prato,Maurizio Prato,Víctor F. Puntes,Vincent M. Rotello,Amila Samarakoon,Raymond E. Schaak,Youqing Shen,Sebastian Sjöqvist,Andre G. Skirtach,Andre G. Skirtach,Mahmoud Soliman,Molly M. Stevens,Hsing-Wen Sung,Ben Zhong Tang,Rainer Tietze,Buddhisha Udugama,J. Scott VanEpps,Tanja Weil,Tanja Weil,Paul S. Weiss,Itamar Willner,Yuzhou Wu,Yuzhou Wu,Lily Yang,Zhao Yue,Qian Zhang,Qiang Zhang,Xian-En Zhang,Yuliang Zhao,Xin Zhou,Wolfgang J. Parak +91 more
TL;DR: An overview of recent developments in nanomedicine is provided and the current challenges and upcoming opportunities for the field are highlighted and translation to the clinic is highlighted.