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Journal ArticleDOI

Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.

TLDR
It is suggested that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.
Abstract
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.

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Citations
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Journal ArticleDOI

The effect of azoospermia factor microdeletions on intracytoplasmic sperm injection results in azoospermia patients

TL;DR: In this article , the frequency of microdeletion in azoospermia patients who underwent microTESE was found to be significantly lower in the micro-deletions patient group compared to the control group.
Book ChapterDOI

The Human Y Chromosome

TL;DR: Results suggest that SRY is the testis-determining gene in man and its mouse homolog Sry is pivotal in murine testicular induction, suggesting that a gene on the Y governs male sex differentiation in mammals.
Journal Article

Effect of Alcohol and Nicotine on Fertility of Male Albino Mice

TL;DR: Remarkable changes were observed in the RAPD profiles, based on difference in band pattern profile as observed in alcohol treated and nicotine induced cases compared to controls; thereby clearly indicating the effect of recreational drug on the genome of the host in comparison to untreated controls.
References
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Journal ArticleDOI

A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.

TL;DR: Data from a chromosome examination of 14,069 consecutive newborn infants is presented, finding 294 babies with a major chromosome abnormality or distinctive marker chromosomes.
Journal ArticleDOI

Possible role for H--Y antigen in the primary determination of sex.

TL;DR: The part that the X chromosome plays in male sexual differentiation has been clarified at the level of an individual gene situated on this chromosome.
Journal ArticleDOI

A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities

TL;DR: The results of the present study when combined with five other comparable studies, thus comprising a total of 46,150 newborn infants, indicates that the frequency of major chromosome abnormalities is between 1:150 and 1:200 live-born babies.
Journal ArticleDOI

Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.

TL;DR: The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an infant born at the Albert Einstein College Hospital, Bronx, New York, and are consistent with the expectations of the Hardy-Weinberg law.
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