Journal ArticleDOI
Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.
TLDR
It is suggested that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.Abstract:
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.read more
Citations
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Book ChapterDOI
Formal Genetics of Humans: Linkage Analysis and Gene Clusters
TL;DR: It was the great achievement of Morgan and his school in the first two decades of the twentieth century to exploit linkage for localizing genes relative to each other on chromosomes and developing gene maps in the fruit fly Drosophila melanogaster.
Book ChapterDOI
Anomalies of the Y Chromosome
Matheus Roque,Igor Faria Dutra +1 more
TL;DR: Although rare in the general population, Y-chromosome microdeletions may be present in up to 7% of severe oligozoospermic and in approximately 15% of azoospermic men, in general, patients presenting with a Y- Chromosomemicrodeletion are asymptomatic, although they may present with a reduction in testicular volume.
Journal ArticleDOI
Pilot study for early prognosis of Azoospermia in relation to Y-STR Profiling
TL;DR: Five haplotypes in four different Y-STR loci were found to possess significantly higher occurrence percentages in Azoospermic than in fertile Saudi individuals, which can serve as a group of pre-diagnostic markers for early prognosis of Azoospermia in Saudi population.
Journal ArticleDOI
La nutraceutiques (alicaments) et compléments alimentaires dans le traitement de l’infertilité masculine
Frank Comhaire,Ahmed Mahmoud +1 more
TL;DR: Evidence is provided that food supplementation with particular substances can improve semen quality and function of subfertile men and increase the probability of spontaneous conception and successful pregnancy.
Posted ContentDOI
Insight into Genetic × Epidemiological factors in male infertility: synergistic effect of AZFc partial deletions and habits of smokeless-chewing tobacco
TL;DR: In this paper , the Y chromosome AZF partial deletions exhibit variations in its association with male infertility across the population divides, and intriguing results showed that the gr/gr deletion was frequent among azoospermic and oligozoospermic subjects, and b1/b3 deletions were detected to be significant among severe-oligozoo-permic men (P = 0.0405).
References
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Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.
TL;DR: Data from a chromosome examination of 14,069 consecutive newborn infants is presented, finding 294 babies with a major chromosome abnormality or distinctive marker chromosomes.
Journal ArticleDOI
Possible role for H--Y antigen in the primary determination of sex.
TL;DR: The part that the X chromosome plays in male sexual differentiation has been clarified at the level of an individual gene situated on this chromosome.
Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities
TL;DR: The results of the present study when combined with five other comparable studies, thus comprising a total of 46,150 newborn infants, indicates that the frequency of major chromosome abnormalities is between 1:150 and 1:200 live-born babies.
Journal ArticleDOI
Structural abnormalities of the Y chromosome in man.
Patricia A. Jacobs,A. Ross +1 more
Journal ArticleDOI
Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.
TL;DR: The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an infant born at the Albert Einstein College Hospital, Bronx, New York, and are consistent with the expectations of the Hardy-Weinberg law.
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