Journal ArticleDOI
Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.
TLDR
It is suggested that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.Abstract:
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.read more
Citations
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Journal Article
Cytogenetic and Y Chromosome Microdeletions Screening in Tunisian Infertile Men
TL;DR: It is revealed that testicular and somatic LDH-A mRNAs differ only in their distinct 5´ non-coding exons of 174 and 78 nucleotides, respectively.
Journal ArticleDOI
Y-Chromosome Microdeletion Analysis in Infertile Men from Upper Egypt
Ashraf Ahmed Abd El-Latif,Essameldin Abdelaziz Nada,Ramadan Saleh Abdo,Manal O. El Hamshary,Kamal Shaeer +4 more
TL;DR: There was no significant difference between patients with AZF deletions and azoospermic men without deletions as regards testicular volume and serum levels of FSH, LH, testosterone and prolactin, suggesting microdeletions of Y chromosome may play a role in pathogenesis of non-obstructive azoOSpermia.
Effects of Y chromosome Microdeletions on Male Fertility
Hesamoddin Sajadi,Neda Taghizabet,Fereshteh Aliakbari,Fatemeh Rezaei-Tazangi,Mohammad Ali Sedighi Gilani +4 more
TL;DR: Y chromosomal microdeletions emerged as the most frequent structural chromosome anomaly associated with the quantitative reduction of sperm.
References
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Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.
TL;DR: Data from a chromosome examination of 14,069 consecutive newborn infants is presented, finding 294 babies with a major chromosome abnormality or distinctive marker chromosomes.
Journal ArticleDOI
Possible role for H--Y antigen in the primary determination of sex.
TL;DR: The part that the X chromosome plays in male sexual differentiation has been clarified at the level of an individual gene situated on this chromosome.
Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities
TL;DR: The results of the present study when combined with five other comparable studies, thus comprising a total of 46,150 newborn infants, indicates that the frequency of major chromosome abnormalities is between 1:150 and 1:200 live-born babies.
Journal ArticleDOI
Structural abnormalities of the Y chromosome in man.
Patricia A. Jacobs,A. Ross +1 more
Journal ArticleDOI
Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.
TL;DR: The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an infant born at the Albert Einstein College Hospital, Bronx, New York, and are consistent with the expectations of the Hardy-Weinberg law.
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