Journal ArticleDOI
Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.
TLDR
It is suggested that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.Abstract:
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.read more
Citations
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Deletions within the azoospermia factor subregions of the Y chromosome in Hong Kong Chinese men with severe male-factor infertility: controlled clinical study.
TL;DR: Deletions within the azoospermia factor subregions of the Y chromosome are associated with severe male-factor infertility in Hong Kong Chinese men.
Journal ArticleDOI
Unique signatures of natural background radiation on human Y chromosomes from Kerala, India.
TL;DR: Exposure to high levels of NBR correlated with several interstitial polymorphisms of the human Y chromosome, suggesting a possible innate mechanism protecting the germline DNA from the NBR.
Journal ArticleDOI
DEAD-Box RNA helicases in animal gametogenesis
TL;DR: The review summarizes a current knowledge about a role of RNA helicases in the development and maintenance of gamenogenesis in eukaryotes and focused on three RNA helicase family members that contain characteristic amino acid sequence motifs (DEAD box) and perform substantial conserved functions in the germinal tissues of various species from Drosophila to human.
Journal ArticleDOI
Prevalence of the Aurora kinase C c.144delC mutation in infertile Moroccan men.
Abdelmajid Eloualid,Hassan Rouba,Houria Rhaissi,Abdelhamid Barakat,Noureddine Louanjli,Anu Bashamboo,Ken McElreavey +6 more
TL;DR: The data indicate that the AURKC c.144delC mutation has a relatively high carrier frequency in the Moroccan population; thus, screening for this deletion in infertile men with a high percentage of large-headed and multiflagellar spermatozoa is recommended.
Journal ArticleDOI
Developmental stage‐specific expression of Rbm suggests its involvement in early phases of spermatogenesis
Jungmin Lee,Jinpyo Hong,Euisu Kim,Kyungjin Kim,Soo Woong Kim,Hanumanthappa Krishnamurthy,Sanny S. W. Chung,Debra J. Wolgemuth,Kunsoo Rhee +8 more
TL;DR: Observations suggest that Rbm functions in early but not later stages of male germ cell development, including haploid germ cells.
References
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Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.
TL;DR: Data from a chromosome examination of 14,069 consecutive newborn infants is presented, finding 294 babies with a major chromosome abnormality or distinctive marker chromosomes.
Journal ArticleDOI
Possible role for H--Y antigen in the primary determination of sex.
TL;DR: The part that the X chromosome plays in male sexual differentiation has been clarified at the level of an individual gene situated on this chromosome.
Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities
TL;DR: The results of the present study when combined with five other comparable studies, thus comprising a total of 46,150 newborn infants, indicates that the frequency of major chromosome abnormalities is between 1:150 and 1:200 live-born babies.
Journal ArticleDOI
Structural abnormalities of the Y chromosome in man.
Patricia A. Jacobs,A. Ross +1 more
Journal ArticleDOI
Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.
TL;DR: The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an infant born at the Albert Einstein College Hospital, Bronx, New York, and are consistent with the expectations of the Hardy-Weinberg law.
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