Journal ArticleDOI
Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm.
TLDR
It is suggested that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.Abstract:
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.read more
Citations
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Posted ContentDOI
Diverse Monogenic Subforms of Human Spermatogenic Failure
TL;DR: The most advanced classification of NOA subforms is based on simple description of testis histology as mentioned in this paper , which is the most severe form of male infertility and typically incurable with current medicine.
Book ChapterDOI
Genetics for the Clinician
TL;DR: Male reproductive medicine and surgery have seen notable advances in the past several years, but most magnificent achievements have involved strategies to compensate for inherent deficiencies in the system, such as anatomical/structural disease that prevents natural conception or inadequate spermatogenesis that essentially precludes paternity through intercourse alone.
Journal ArticleDOI
Verification of a cryptic t(Y;15) translocation in a male with an apparent 45,X karyotype
TL;DR: In this article , the authors explored the genetic aetiology of an infertile male with an apparent 45,X karyotype, which was subsequently verified as cryptic translocation between chromosomes Y and 15.
Journal ArticleDOI
The Indication of ICSI
TL;DR: Surprisingly, among those in split cycle who had had fertilization failure on previous conventional IVF trial, no significant difference was found in fertilization rates between conventional IVf eggs and ICSI eggs, suggesting split cycle might be a better choice.
Journal ArticleDOI
Molecular genetic study on AZFa and AZFb sub region microdeletions in infertile men of Gujarat, Western India
Mili Nailwal,Jenabhai B. Chauhan +1 more
TL;DR: It is identified that Y chromosome microdeletion screening is necessary in Gujarati population to rule out genetic causes responsible for male infertility and to proceed for assisted reproductive technology.
References
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Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities.
TL;DR: Data from a chromosome examination of 14,069 consecutive newborn infants is presented, finding 294 babies with a major chromosome abnormality or distinctive marker chromosomes.
Journal ArticleDOI
Possible role for H--Y antigen in the primary determination of sex.
TL;DR: The part that the X chromosome plays in male sexual differentiation has been clarified at the level of an individual gene situated on this chromosome.
Journal ArticleDOI
A cytogenetic survey of 14,069 newborn infants. I. Incidence of chromosome abnormalities
TL;DR: The results of the present study when combined with five other comparable studies, thus comprising a total of 46,150 newborn infants, indicates that the frequency of major chromosome abnormalities is between 1:150 and 1:200 live-born babies.
Journal ArticleDOI
Structural abnormalities of the Y chromosome in man.
Patricia A. Jacobs,A. Ross +1 more
Journal ArticleDOI
Chromosome polymorphism in a human newborn population. II. Potentials of polymorphic chromosome variants for characterizing the idiogram of an individual.
TL;DR: The baseline data presented here reinforce the view that polymorphic chromosome characteristics are very useful markers for characterizing the karyotype of an infant born at the Albert Einstein College Hospital, Bronx, New York, and are consistent with the expectations of the Hardy-Weinberg law.
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