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Open AccessJournal ArticleDOI

OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.
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This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.

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Citations
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Efficacy of intra-articular hyaluronic acid injections in hip osteoarthritis: a meta-analysis of randomized controlled trials.

Bei Wu, +2 more
- 18 Sep 2017 - 
TL;DR: Intra-articular HA in hip OA can significantly reduce pain and improve functional recovery when compared with the condition before treatment, however, there seems no significant difference between HA and saline or other treatments.
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Dabigatran etexilate and concomitant use of non-steroidal anti-inflammatory drugs or acetylsalicylic acid in patients undergoing total hip and total knee arthroplasty: No increased risk of bleeding

TL;DR: For both NSAIDs and ASA there was no significant difference in bleeding between patients with and without concomitant therapy in any treatment arm, suggesting that no increased major bleeding risk exists when dabigatran etexilate is administered with NSAID or ASA.
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Current state of unloading braces for knee osteoarthritis

TL;DR: Current biomechanical evidence suggests that unloading of the affected knee compartment does not significantly hinder disease progression, and overall improvements in parameters such as pain, instability, and quality of life are revealed.
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Effect of Soft Braces on Pain and Physical Function in Patients With Knee Osteoarthritis: Systematic Review With Meta-Analyses

TL;DR: Current available evidence indicates that soft braces have moderate effects on pain and small to moderateeffects on self-reported physical function in knee osteoarthritis, and highlight the importance of soft braces as a technique to improve pain and physicalfunction in both the short- and long-term.
References
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Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Assessing the quality of reports of randomized clinical trials : is blinding necessary?

TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
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Grading quality of evidence and strength of recommendations.

TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
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Primary, Secondary, and Meta-Analysis of Research

TL;DR: The meta-analysis of research as discussed by the authors is an important feature of the research and evaluation enterprise, and it has been widely used in the field of computer science and computer engineering, especially in the context of education.
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