OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
Reads0
Chats0
TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
Citations
More filters
Journal ArticleDOI
Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions
Elizaveta Kon,Roberto Buda,Giuseppe Filardo,Alessandro Di Martino,Antonio Timoncini,Annarita Cenacchi,Pier Maria Fornasari,Sandro Giannini,Maurilio Marcacci +8 more
TL;DR: The preliminary results indicate that the treatment with PRP injections is safe and has the potential to reduce pain and improve knee function and quality of live in younger patients with low degree of articular degeneration.
Journal ArticleDOI
Platelet-Rich Plasma Intra-Articular Injection Versus Hyaluronic Acid Viscosupplementation as Treatments for Cartilage Pathology: From Early Degeneration to Osteoarthritis
Elizaveta Kon,Bert R. Mandelbaum,Roberto Buda,Giuseppe Filardo,Marco Delcogliano,Antonio Timoncini,Pier Maria Fornasari,Sandro Giannini,Maurilio Marcacci +8 more
TL;DR: Autologous PRP injections showed more and longer efficacy than HA injections in reducing pain and symptoms and recovering articular function, whereas a worse outcome was obtained in more degenerated joints and in older patients, in whom results similar to those of viscosupplementation have been observed.
Journal ArticleDOI
Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial.
Timothy E. McAlindon,Michael P. LaValley,William F. Harvey,Lori Lyn Price,Jeffrey B. Driban,Ming Zhang,Robert Ward +6 more
TL;DR: 2 years of intra-articular triamcinolone, compared with intra-artsicular saline, resulted in significantly greater cartilage volume loss and no significant difference in knee pain, and these findings do not support this treatment for patients with symptomatic knee osteoarthritis.
Journal ArticleDOI
Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis
Giuseppe Filardo,Elizaveta Kon,Roberto Buda,Antonio Timoncini,Alessandro Di Martino,Annarita Cenacchi,Pier Maria Fornasari,Sandro Giannini,Maurilio Marcacci +8 more
TL;DR: These findings indicate that treatment with PRP injections can reduce pain and improve knee function and quality of life with short-term efficacy, and further studies are needed to confirm these results and understand the mechanism of action.
Journal Article
The economic burden of osteoarthritis.
TL;DR: Despite the need for wide-ranging and up-to-date data on the economics of OA treatment to clarify the most effective treatments and the best use of resources, this area of study has received insufficient research attention.
References
More filters
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Journal ArticleDOI
Assessing the quality of reports of randomized clinical trials : is blinding necessary?
Alejandro R. Jadad,R. A. Moore,Dawn Carroll,C. Jenkinson,David Reynolds,David J. Gavaghan,Henry J McQuay +6 more
TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
Journal ArticleDOI
Grading quality of evidence and strength of recommendations.
David C. Atkins,Dana Best,Peter A. Briss,Martin P Eccles,Yngve Falck-Ytter,Signe Flottorp,Gordon H. Guyatt,Robin Harbour,Margaret C Haugh,David Henry,Suzanne Hill,Roman Jaeschke,Gillian Leng,Alessandro Liberati,Nicola Magrini,James Mason,Philippa Middleton,Jacek Mrukowicz,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Tessa Tan-Torres Edejer,H. Varonen,Gunn Elisabeth Vist,John W Williams,Stephanie Zaza +26 more
TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
Journal ArticleDOI
Primary, Secondary, and Meta-Analysis of Research
TL;DR: The meta-analysis of research as discussed by the authors is an important feature of the research and evaluation enterprise, and it has been widely used in the field of computer science and computer engineering, especially in the context of education.
Related Papers (5)
EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)
K M Jordan,Nigel K Arden,M Doherty,Bernard Bannwarth,Johannes W. J. Bijlsma,Paul Dieppe,K. P. Günther,H J Hauselmann,Gabriel Herrero-Beaumont,P Kaklamanis,Stefan Lohmander,Burkhard F. Leeb,Michel Lequesne,Bernard Mazières,E. Martin-Mola,Karel Pavelka,Adrian Pendleton,Leonardo Punzi,U Serni,B Swoboda,G. Verbruggen,I Zimmerman-Gorska,Maxime Dougados +22 more
Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
Roy D. Altman,E. Asch,Daniel Bloch,Giles G. Bole,David G. Borenstein,Kenneth D. Brandt,Wallace C. Christy,Cooke Td,Robert A. Greenwald,Marc C. Hochberg,David S. Howell,David L. Kaplan,William J. Koopman,Selden Longley,Henry J. Mankin,Dennis J. McShane,Thomas A. Medsger,Robert F. Meenan,William M. Mikkelsen,Roland W. Moskowitz,William A. Murphy,B. Rothschild,Mark R. Segal,Leon Sokoloff,Frederick Wolfe +24 more