OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
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Viscosupplementation for Osteoarthritis of the Knee
TL;DR: A 67-year-old woman with osteoarthritis of the right knee seeks guidance regarding the possible benefit of hyaluronate injection.
Journal ArticleDOI
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial.
Amy S. Chappell,Melissa J. Ossanna,Hong Liu-Seifert,Smriti Iyengar,Vladimir Skljarevski,Linda Chunhong Li,Robert M. Bennett,Harry Collins +7 more
TL;DR: Duloxetine was superior to placebo on the primary efficacy measure (weekly mean 24‐h pain scores) beginning at Week 1 and continuing through the treatment period (P ⩽ .05), and there was a significant improvement in the WOMAC physical functioning subscale and several other secondary outcomes.
Journal ArticleDOI
Impact of Obesity and Knee Osteoarthritis on Morbidity and Mortality in Older Americans
Elena Losina,Rochelle P. Walensky,William M. Reichmann,Holly L. Holt,Hanna Gerlovin,Daniel H. Solomon,Joanne M. Jordan,David J. Hunter,Lisa G. Suter,Alexander M. Weinstein,A. David Paltiel,Jeffrey N. Katz +11 more
TL;DR: The model findings suggested that reversing obesity prevalence to levels seen 10 years ago would avert 178,071 cases of coronary heart disease, 889,872 cases of diabetes, and 111,206 total knee replacements, with black and Hispanic women experiencing disproportionate losses.
Journal ArticleDOI
A randomised, double-blind, controlled trial comparing two intra-articular hyaluronic acid preparations differing by their molecular weight in symptomatic knee osteoarthritis
Francis Berenbaum,Joachim Grifka,Sara Cazzaniga,Massimo D'Amato,Giampaolo Giacovelli,Xavier Chevalier,François Rannou,Lucio C. Rovati,Emmanuel Maheu +8 more
TL;DR: Treatment with 3-weekly injections of intermediate MW HA may be superior to low MW HA on knee OA symptoms over 6 months, with similar safety.
Journal ArticleDOI
Efficacy and safety of Tapentadol extended release compared with oxycodone controlled release for the management of moderate to severe chronic pain related to osteoarthritis of the knee: a randomized, double-blind, placebo- and active-controlled phase III study.
Marc Afilalo,Mila Etropolski,Brigitte Kuperwasser,Kathy Kelly,Akiko Okamoto,Ilse Van Hove,A. Steup,Bernd Lange,Christine Rauschkolb,Juergen Haeussler +9 more
TL;DR: Treatment with tapentadol ER 100–250 mg twice daily or oxycodone HCl CR 20–50mg twice daily was effective for the management of moderate to severe chronic osteoarthritis-related knee pain, with substantially lower incidences of gastrointestinal-related TEAEs associated with treatment withTapentadl ER than with oxy codone CR.
References
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