OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
Citations
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Effectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee.
Chao Zeng,Jie Wei,Hui Li,Yilun Wang,Dongxing Xie,Tuo Yang,Shu-guang Gao,Yusheng Li,Wei Luo,Guanghua Lei +9 more
TL;DR: Evidence is provided for the symptomatic efficacy of glucosamine plus chondroitin in the treatment of knee OA and celecoxib is most likely to be the best treatment option, followed by the combination group.
Journal ArticleDOI
MicroRNA-181 inhibits proliferation and promotes apoptosis of chondrocytes in osteoarthritis by targeting PTEN.
TL;DR: MiR-181 could up-regulate the expressions of caspase-3, PARP, M MP-2, and MMP-9, and thereby inhibit cell proliferation and promote apoptosis of chondrocytes in OA by targeting PTEN.
Journal Article
Hip viscosupplementation under ultra-sound guidance riduces NSAID consumption in symptomatic hip osteoarthritis patients in a long follow-up. Data from Italian registry.
Alberto Migliore,Mauro Granata,S. Tormenta,Bruno Laganà,Prisco Piscitelli,Emanuele Bizzi,U. Massafra,A. Alimonti,C Maggi,R De Chiara,F Iannessi,Antonino Sanfilippo,R Sotera,P Scapato,S Carducci,P Persod,S. Denaro,M Camminiti,M G Pagano,Gianluca Bagnato,Giovanni Iolascon +20 more
TL;DR: It is pointed out that intraarticular hyaluronan preparations provide OA pain relief and reduce NSAIDs consumption in a large cohort of patients for a long period of follow-up, and is associated with a low incidence of adverse effects.
Journal ArticleDOI
Loaded Cartilage T2 Mapping in Patients with Hip Dysplasia
TL;DR: Cartilage T2 mapping with loading during MR imaging enabled the detection of site-specific changes in cartilage T1 in dysplastic hips.
Journal ArticleDOI
Manual therapy, exercise therapy, or both, in addition to usual care, for osteoarthritis of the hip or knee. 2: economic evaluation alongside a randomized controlled trial.
TL;DR: In this study, exercise therapy and manual therapy were more cost effective than usual care at policy relevant values of willingness-to-pay from both the perspective of the health system and society.
References
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TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
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