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Open AccessJournal ArticleDOI

OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.
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This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.

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Comparison of the clinical effectiveness of thermal cure and rehabilitation in knee osteoarthritis. A randomized therapeutic trial

TL;DR: In this paper, the benefits of thermal cure and non-thermal rehabilitation in treatment of knee osteoarthritis (KOA) were compared, and crenobalneotherapy had resulted, at 12 months, in more pronounced long-term improvement of the painful symptoms of KOA.
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Validation of a Bowel Function Diary for Assessing Opioid-Induced Constipation

TL;DR: Number of spontaneous bowel movements is a valid measure for differentiating opioid-treated patients with and without constipation, and BF-Diary items are generally reliable and valid assessments for OIC research.
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"It looks after me": how older patients make decisions about analgesics for osteoarthritis.

TL;DR: To explore the key motivators behind selection of analgesics by patients with osteoarthritis, nonsteroidal antiinflammatory drugs [NSAIDs], acetaminophen, and complementary medications [CMs] are examined.
Journal Article

Efficacy of Home-Based Kinesthesia, Balance & Agility Exercise Training Among Persons with Symptomatic Knee Osteoarthritis

TL;DR: The results indicate that KBA, RT, or a combination of the two administered as home exercise programs are effective in improving symptoms and quality of life among persons with knee OA.
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Exercise: necessary but not sufficient for improving function and preventing disability?

TL;DR: Current and recent evidence shows little to no impact of exercise on the prevention of disability and different strategies need to be developed to address disability more directly.
References
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Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Assessing the quality of reports of randomized clinical trials : is blinding necessary?

TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
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Grading quality of evidence and strength of recommendations.

TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
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Primary, Secondary, and Meta-Analysis of Research

TL;DR: The meta-analysis of research as discussed by the authors is an important feature of the research and evaluation enterprise, and it has been widely used in the field of computer science and computer engineering, especially in the context of education.
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