OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
Citations
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The effect on knee-joint load of instruction in analgesic use compared with neuromuscular exercise in patients with knee osteoarthritis: study protocol for a randomized, single-blind, controlled trial (the EXERPHARMA trial)
Brian Clausen,Anders Holsgaard-Larsen,Jens Søndergaard,Robin Christensen,Robin Christensen,Thomas P. Andriacchi,Thomas P. Andriacchi,Ewa M. Roos +7 more
TL;DR: These findings will help determine whether 8 weeks of neuromuscular exercise is superior to optimized use of analgesics and antiinflammatory drugs regarding knee-joint load, pain and physical function in people with mild to moderate knee osteoarthritis.
Journal ArticleDOI
Efficacy of multimodal, systematic non-surgical treatment of knee osteoarthritis for patients not eligible for a total knee replacement: a study protocol of a randomised controlled trial
Søren Thorgaard Skou,Ewa M. Roos,Mogens Berg Laursen,Michael Skovdal Rathleff,Michael Skovdal Rathleff,Lars Arendt-Nielsen,Ole Simonsen,Sten Rasmussen,Sten Rasmussen +8 more
TL;DR: If an optimised, combined non-surgical treatment programme results in greater improvements in pain, function and quality of life in comparison with usual care in patients with KOA who are not eligible for total knee arthroplasty (TKA).
Journal Article
The powerful placebo effect in osteoarthritis
TL;DR: It is found that people with OA respond better to treatment which targets on both peripheral and central pain abnormalities, and it is also found that placebo per se is very effective for OA.
Journal ArticleDOI
Opioids in rheumatic diseases.
TL;DR: The role of opioids in chronic rheumatic diseases is focused on and the peripheral effects of opioids on pain and inflammation in rhematic diseases will be outlined.
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Improvement in quality of life with use of an unloader knee brace in active patients with OA: a prospective cohort study.
TL;DR: Braces specifically designed to unload the degenerative compartment of the knee can be an effective treatment to decrease pain and maintain activity level to increase overall physical health.
References
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Alejandro R. Jadad,R. A. Moore,Dawn Carroll,C. Jenkinson,David Reynolds,David J. Gavaghan,Henry J McQuay +6 more
TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
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Grading quality of evidence and strength of recommendations.
David C. Atkins,Dana Best,Peter A. Briss,Martin P Eccles,Yngve Falck-Ytter,Signe Flottorp,Gordon H. Guyatt,Robin Harbour,Margaret C Haugh,David Henry,Suzanne Hill,Roman Jaeschke,Gillian Leng,Alessandro Liberati,Nicola Magrini,James Mason,Philippa Middleton,Jacek Mrukowicz,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Tessa Tan-Torres Edejer,H. Varonen,Gunn Elisabeth Vist,John W Williams,Stephanie Zaza +26 more
TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
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