OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
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A community-wide campaign to promote physical activity in middle-aged and elderly people: a cluster randomized controlled trial
Masamitsu Kamada,Masamitsu Kamada,Jun Kitayuguchi,Shigeru Inoue,Yoshiki Ishikawa,Hiromu Nishiuchi,Shimpei Okada,Kazuhiro Harada,Kazuhiro Harada,Hiroharu Kamioka,Kuninori Shiwaku +10 more
TL;DR: This cluster RCT showed that the CWC did not promote physical activity in 1 year, and significant differences were observed in awareness and knowledge between intervention and control groups as short-term impacts of the campaign.
Journal ArticleDOI
The role of arthroscopy in the management of knee osteoarthritis
TL;DR: For example, this paper showed that patients who underwent arthroscopic partial meniscectomy for a degenerative meniscal tear generally did not show more improvement than those who underwent sham meniscal resection or an intensive course of physical therapy.
Review article Symptom and structure modification in osteoarthritis with pharmaceutical-grade chondroitin sulfate: what's the evidence?
TL;DR: Chondroitin sulfate is recommended by several guidelines from international societies in the management of knee and hip OA and its safety profile is favorable when compared with many other therapies used in OA.
Journal ArticleDOI
Emerging Trend in the Pharmacotherapy of Osteoarthritis.
TL;DR: emerging OA drugs such as bone morphogenetic protein-7 (BMP-7), fibroblast growth factor-18 (FGF-18), human serum albumin (HSA), interleukin-1 (IL-1) inhibitor, β-Nerve growth factor (β-NGF) antibody, matrix extracellular phosphoglycoprotein (MEPE) and inverse agonist of retinoic acid-related orphan receptor alpha (RORα) etc
Journal ArticleDOI
Osteoarthritis of the knee and hip. Part I: aetiology and pathogenesis as a basis for pharmacotherapy.
TL;DR: To obtain insight into the extent of pathological changes in hip and knee OA, current literature on the pathogenesis of this state is reviewed as a basis for current pharmacotherapy options.
References
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Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Assessing the quality of reports of randomized clinical trials : is blinding necessary?
Alejandro R. Jadad,R. A. Moore,Dawn Carroll,C. Jenkinson,David Reynolds,David J. Gavaghan,Henry J McQuay +6 more
TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
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Grading quality of evidence and strength of recommendations.
David C. Atkins,Dana Best,Peter A. Briss,Martin P Eccles,Yngve Falck-Ytter,Signe Flottorp,Gordon H. Guyatt,Robin Harbour,Margaret C Haugh,David Henry,Suzanne Hill,Roman Jaeschke,Gillian Leng,Alessandro Liberati,Nicola Magrini,James Mason,Philippa Middleton,Jacek Mrukowicz,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Tessa Tan-Torres Edejer,H. Varonen,Gunn Elisabeth Vist,John W Williams,Stephanie Zaza +26 more
TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
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Primary, Secondary, and Meta-Analysis of Research
TL;DR: The meta-analysis of research as discussed by the authors is an important feature of the research and evaluation enterprise, and it has been widely used in the field of computer science and computer engineering, especially in the context of education.
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