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OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.
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This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.

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CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016

TL;DR: This guideline is intended to improve communication about benefits and risks of opioids for chronic pain, improve safety and effectiveness of pain treatment, and reduce risks associated with long-term opioid therapy.
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CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016.

TL;DR: This guideline is intended to improve communication between clinicians and patients about the risks and benefits of opioid therapy for chronic pain, improve the safety and effectiveness of pain treatment, and reduce the risks associated with long-term opioid therapy, including opioid use disorder, overdose, and death.
References
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Journal ArticleDOI

Intra-articular treatment of hip osteoarthritis : a randomized trial of hyaluronic acid, corticosteroid, and isotonic saline

TL;DR: Patients treated with corticosteroids experienced significant improvement during the 3 months of intervention, with an effect size indicating a moderate clinical effect, although a similar significant result following treatment with HA could not be shown.
Journal Article

A metaanalysis of severe upper gastrointestinal complications of nonsteroidal antiinflammatory drugs.

TL;DR: These data support an association between the use of NSAID and serious upper GI complications, including estimates from different study designs, which must be viewed with caution.
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Articular debridement versus washout for degeneration of the medial femoral condyle: a five-year study

TL;DR: For knees with lesions of the medial femoral condyle of grades 3 or 4, arthroscopic debridement appears to be the treatment of choice with over half the patients free from pain after five years.
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Intra-articular triamcinolone hexacetonide in knee osteoarthritis: factors influencing the clinical response.

TL;DR: THA provided short term pain relief in knee OA and increased benefit was associated with both clinical evidence of joint effusion and successful aspiration of synovial fluid at the time of injection.
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The effectiveness of five strategies for the prevention of gastrointestinal toxicity induced by non-steroidal anti-inflammatory drugs: systematic review

TL;DR: No evidence of effectiveness of H2 receptor antagonists for any primary outcomes is found, and misoprostol, COX-2 specific and selective NSAIDs, and probably proton pump inhibitors significantly reduce the risk of symptomatic ulcers, but data quality is low.
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