OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
Citations
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Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult?
TL;DR: The risks and benefits of NSAID therapy are discussed, its mechanism of action as the source of adverse effects is reviewed, and recommendations for maximizing NSAID safety are provided, particularly in older patients.
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Diagnosis and treatment of osteoarthritis.
TL;DR: Osteoarthritis presents in primary and secondary forms, and the most common symptom is pain.
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Stem cell injections in knee osteoarthritis: a systematic review of the literature
Haiko I M F L Pas,Marinus Winters,Hidde J. Haisma,Martinus J. J. Koenis,Johannes L. Tol,Maarten H. Moen +5 more
TL;DR: Six trials with high risk of bias showed level-3 or level-4 evidence in favour of stem cell injections in KOA, and in the absence of high-level evidence, stem cell therapy for KOA is not recommended.
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Stability of medial opening wedge high tibial osteotomy: a failure analysis
TL;DR: Medial opening wedge high tibial osteotmy (HTO) is often used to treat varus gonarthrosis in young, active, highly demanding patients, although it has many pitfalls, which were evaluated in a consecutive cohort of patients.
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Intra-articular drug delivery systems for the treatment of rheumatic diseases: A review of the factors influencing their performance
TL;DR: The present review article summarises the research done in the field of drug delivery systems for i-a.
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