OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines
Weiya Zhang,R W Moskowitz,George Nuki,S Abramson,R D Altman,Nigel K Arden,Sita M A Bierma-Zeinstra,K D Brandt,P Croft,Michael Doherty,Maxime Dougados,Marc C. Hochberg,David J. Hunter,K Kwoh,L S Lohmander,Peter Tugwell +15 more
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TLDR
Twenty-five carefully worded recommendations have been generated based on a critical appraisal of existing guidelines, a systematic review of research evidence and the consensus opinions of an international, multidisciplinary group of experts for the management of hip and knee osteoarthritis.About:
This article is published in Osteoarthritis and Cartilage.The article was published on 2008-02-01 and is currently open access. It has received 2616 citations till now. The article focuses on the topics: Evidence-based medicine & Critical appraisal.read more
Citations
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Hyaluronan for knee osteoarthritis: an updated meta-analysis of trials with low risk of bias
Pascal Richette,Xavier Chevalier,Hang-Korng Ea,Hang-Korng Ea,Florent Eymard,Yves Henrotin,Paul Ornetti,Jérémie Sellam,Michel Cucherat,Marc Marty +9 more
TL;DR: This meta-analysis of high-quality trials of IAHA versus placebo shows that IAHA provides a moderate but real benefit for patients with KOA.
Journal ArticleDOI
Intra-articular hyaluronic acid injection versus oral non-steroidal anti-inflammatory drug for the treatment of knee osteoarthritis: a multi-center, randomized, open-label, non-inferiority trial
Muneaki Ishijima,Toshitaka Nakamura,Katsuji Shimizu,Kunihiko Hayashi,Hiraku Kikuchi,Satoshi Soen,Go Omori,Toshihiko Yamashita,Yuji Uchio,Junji Chiba,Yuki Ideno,Mitsuaki Kubota,Hisashi Kurosawa,Kazuo Kaneko +13 more
TL;DR: The early efficacy of IA-HA is suggested to be not inferior to that of NSAIDs, and that the safety of the early phase of IA -HA is superior to thatof NSAIDs for patients with knee OA.
Journal ArticleDOI
Projecting the direct cost burden of osteoarthritis in Canada using a microsimulation model.
Behnam Sharif,Jacek A. Kopec,Nick Bansback,M. Mushfiqur Rahman,William M. Flanagan,Hubert Wong,Philippe Finès,Aslam H. Anis +7 more
TL;DR: In this article, the authors used administrative health data from the province of British Columbia (BC), Canada, a survey of a random sample of BC residents diagnosed with OA (Ministry of Health of BC data), Canadian Institute of Health Information (CIHI) cost data and literature estimates to populate a microsimulation model.
Journal ArticleDOI
A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis
TL;DR: This review is intended to provide physicians with an overview of the benefits and risks associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in the management of their patients with mild-to-moderate OA pain.
Journal ArticleDOI
Intra-articular injections of expanded mesenchymal stem cells with and without addition of platelet-rich plasma are safe and effective for knee osteoarthritis.
Ricardo Bastos,Marcelo Mathias,Renato Andrade,Raquel Bastos,Alex Balduino,Vinicius Schott,Scott A. Rodeo,João Espregueira-Mendes +7 more
TL;DR: Intra-articular injections of expanded MSCs alone or in combination with PRP are safe and have a beneficial effect on symptoms in patients with symptomatic knee osteoarthritis, without requiring hospitalization.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test
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Alejandro R. Jadad,R. A. Moore,Dawn Carroll,C. Jenkinson,David Reynolds,David J. Gavaghan,Henry J McQuay +6 more
TL;DR: An instrument to assess the quality of reports of randomized clinical trials (RCTs) in pain research is described and its use to determine the effect of rater blinding on the assessments of quality is described.
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