Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
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TLDR
Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark display various pharmacological effects while being devoid of prominent toxicity and are promising leading compounds for the development of new multi-targeting bioactive agents.Abstract:
Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark. In particular the lupane-, oleanane-, and ursane triterpenes display various pharmacological effects while being devoid of prominent toxicity. Therefore, these triterpenes are promising leading compounds for the development of new multi-targeting bioactive agents. Screening of 39 plant materials identified triterpene rich (> 0.1% dry matter) plant parts. Plant materials with high triterpene concentrations were then used to obtain dry extracts by accelerated solvent extraction resulting in a triterpene content of 50 - 90%. Depending on the plant material, betulin (birch bark), betulinic acid (plane bark), oleanolic acid (olive leaves, olive pomace, mistletoe sprouts, clove flowers), ursolic acid (apple pomace) or an equal mixture of the three triterpene acids (rosemary leaves) are the main components of these dry extracts. They are quantitatively characterised plant extracts supplying a high concentration of actives and therefore can be used for development of phytopharmaceutical formulations.read more
Citations
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Comparison of the Triterpenoid Content of Berries and Leaves of Lingonberry Vaccinium vitis-idaea from Finland and Poland
TL;DR: The most striking difference concerned the occurrence of fernenol and taraxasterol, which were found to be the major triterpenol in lingonberry leaves of Finnish and Polish origin, respectively.
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An Evidence-Based Systematic Review of Rosemary (Rosmarinus officinalis) by the Natural Standard Research Collaboration
Catherine Ulbricht,Tracee Rae Abrams,Ashley Brigham,James Ceurvels,Jessica Clubb,Whitney Curtiss,Catherine DeFranco Kirkwood,Nicole Giese,Kevin Hoehn,Ramon Iovin,Richard Isaac,Erica Rusie,Jill M. Grimes Serrano,Minney Varghese,Wendy Weissner,Regina C. Windsor +15 more
TL;DR: An evidence-based systematic review of rosemary (Rosmarinus officinalis), including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.
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Understanding the potential benefits of thyme and its derived products for food industry and consumer health: From extraction of value-added compounds to the evaluation of bioaccessibility, bioavailability, anti-inflammatory, and antimicrobial activities
José M. Lorenzo,Amin Mousavi Khaneghah,Mohsen Gavahian,Krystian Marszałek,Ismail Eş,Paulo E.S. Munekata,Isabel C.F.R. Ferreira,Francisco J. Barba +7 more
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The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications.
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