Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.
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TLDR
Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark display various pharmacological effects while being devoid of prominent toxicity and are promising leading compounds for the development of new multi-targeting bioactive agents.Abstract:
Pentacyclic triterpenes are secondary plant metabolites widespread in fruit peel, leaves and stem bark. In particular the lupane-, oleanane-, and ursane triterpenes display various pharmacological effects while being devoid of prominent toxicity. Therefore, these triterpenes are promising leading compounds for the development of new multi-targeting bioactive agents. Screening of 39 plant materials identified triterpene rich (> 0.1% dry matter) plant parts. Plant materials with high triterpene concentrations were then used to obtain dry extracts by accelerated solvent extraction resulting in a triterpene content of 50 - 90%. Depending on the plant material, betulin (birch bark), betulinic acid (plane bark), oleanolic acid (olive leaves, olive pomace, mistletoe sprouts, clove flowers), ursolic acid (apple pomace) or an equal mixture of the three triterpene acids (rosemary leaves) are the main components of these dry extracts. They are quantitatively characterised plant extracts supplying a high concentration of actives and therefore can be used for development of phytopharmaceutical formulations.read more
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Classification of sugarcane genotypes susceptible and resistant to the initial attack of sugarcane borer Diatraea saccharalis using epicuticular wax composition.
Cleiton Antonio Wartha,Nathália de Aguiar Porto,Adriano Cirino Tomaz,Jussara V. Roque,Mariana Beatriz Teixeira Diniz,Maria Eliana Lopes Ribeiro de Queiroz,Reinaldo F. Teófilo,Márcio Henrique Pereira Barbosa +7 more
TL;DR: In this paper , a greenhouse experiment was performed in a factorial scheme with and without borer infestation using genotypes previously characterized as resistant or susceptible in field-based experiments.
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State-of-the-Art and Opportunities for Bioactive Pentacyclic Triterpenes from Native Mexican Plants
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In-depth Investigation on Triterpenoid Production from the Desert Plants Aloe vera (L.) Burm.f. and Opuntia robusta J.C. Wendl. Prompted by Their Low Specific Methane Production
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OeBAS and CYP716C67 catalyze the biosynthesis of health-beneficial triterpenoids in olive (Olea europaea L.) fruits.
Fiammetta Alagna,James Reed,Ornella Calderini,Ramesha B. Thimmappa,Nicolò G. M. Cultrera,Alice Cattivelli,Davide Tagliazucchi,Soraya Mousavi,Roberto Mariotti,Anne Osbourn,Luciana Baldoni +10 more
TL;DR: In this article , the authors identify and functionally characterize an oxidosqualene cyclase (OeBAS) required for the production of the major triterpene scaffold β-amyrin, the precursor of erythrodiol, oleanolic, and maslinic acids, and a cytochrome P450 (CYP716C67) that mediates 2α oxidation of the oleanane- and ursane-type triter pene scaffolds.
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Lipophilic Bioactive Compounds Transported in Triglyceride-Rich Lipoproteins Modulate Microglial Inflammatory Response
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