Journal ArticleDOI
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis
Jon M. Hanifin,Thurston M,Thurston M,Omoto M,Omoto M,R. Cherill,R. Cherill,Susan J. Tofte,Graeber M,Graeber M +9 more
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TLDR
In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.Abstract:
:Objective– To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. Design: Training of evaluators, application, and assessment over 2 consecutive days. Setting– An academic center. Patients– Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients ≥8 years) and cohort 2 (10 patients <8 years). Interventions– None. Main outcome measure– The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. Results– Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. Conclusions– This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.read more
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Physical activity and mental health among patients with atopic dermatitis or chronic spontaneous urticaria: A cross‐sectional study
M. A. K. Wiis,S. Heilskov,Jennifer A. Sørensen,Henrik Egekvist,Mette Deleuran,Simon Francis Thomsen,Charlotte Vestergaard +6 more
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Blood Cells Count Derived Inflammation Indexes as Predictors of Early Treatment Response to Dupilumab in Patients with Moderate-to-Severe Atopic Dermatitis
Angelo Zinellu,Federica Sucato,Viviana Piras,Gian Mario Addis,Gabriele Biondi,M.A. Montesu,Arduino A. Mangoni,Ciriaco Carru,Pietro Pirina,Panagiotis Paliogiannis,Alessandro G. Fois,Rosanna Satta +11 more
TL;DR: In this paper , the authors investigated the association between pre-specified baseline inflammatory indexes and dupilumab response (≥50% reduction in the EASI 50) at 4 and 16 weeks in a consecutive series of 66 AD patients (38 males and 28 females).
Journal ArticleDOI
“Can you make a definite diagnosis of atopic dermatitis?” in advance of treatment as general pediatricians: ~適切な治療のために, とくに一般小児科医として~
Takuji Murata,Ikuo Okafuji,Tatsuki Fukuie,Yuko Ebishima,Masaki Futamura,Miki Morikawa,Mitsuhiko Nambu +6 more
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Advanced Capnography Sampling Lines May Improve Patient Comfort and Compliance.
TL;DR: In this paper, the authors developed advanced sampling lines, designed to ameliorate the primary factors impacting patient tolerance, which may increase patient compliance with monitoring in non-intubated patients.
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Severity Scoring of Atopic Dermatitis: The SCORAD Index
K.U. Schallreuter,Ch. Levenig,J. Berger,J. Umbert,R.K. Winkelmann,L. Wegener,O. Correia,Olivier Chosidow,P. Saiag,S. Bastuji-Garin,J. Revuz,Jean-Claude Roujeau,R. Situ,D.R. Inman,S.E.G. Fligiel,J. Varani,R.E. Schopf,J. Dobmeyer,T. Dobmeyer,B. Morsches,K. Holubar,G.E. Piérard,O. Bongard,H. Bounameaux,P. Corcuff,J.-L. Lévêque,J. Brasch,E. Christophers,G.T. Nahass,M. Sisto,S.A. Wagner,R.U. Peter,O. Adam,T. Ruzicka,J. McGrath,N.P. Burrows,R. Russell Jones,R.A.J. Eady,S. Veraldi,G. Rizzitelli,G. Lunghi,R. Cardone,R.M. Trüeb,G. Burg,F. Wantke,G. Fleischl,M. Götz,R. Jarisch,G. Tadini,E. Ermacora,S. Cambiaghi,A. Brusasco,R. Cavalli +52 more
TL;DR: Assessment methods for atopic dermatitis are not standardized, and therapeutic studies are difficult to interpret, so consensus on these methods is needed to obtain a consensus on them.
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