scispace - formally typeset
Journal ArticleDOI

The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis

Reads0
Chats0
TLDR
In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.
Abstract
:Objective– To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. Design: Training of evaluators, application, and assessment over 2 consecutive days. Setting– An academic center. Patients– Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients ≥8 years) and cohort 2 (10 patients <8 years). Interventions– None. Main outcome measure– The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. Results– Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. Conclusions– This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.

read more

Citations
More filters
Journal ArticleDOI

Prospective, Randomized Study on the Efficacy and Safety of Local UV-Free Blue Light Treatment of Eczema.

TL;DR: UV-free blue light was safe and effective in the reduction of eczema lesions and the primary end point change from baseline in the mean sum score of the local Eczema Severity Index was more pronounced for the treated area than for the control area.
Journal ArticleDOI

Increased plasma concentration of vascular endothelial growth factor in patients with atopic dermatitis and its relation to disease severity and platelet activation.

TL;DR: It seems that plasma VEGF concentration is not a useful marker of disease severity and, apart from platelets, other cells might also release the cytokine.
Journal ArticleDOI

Clinical Management of Atopic Eczema with Pimecrolimus Cream 1% (Elidel®) in Paediatric Patients

TL;DR: Pimecrolimus is an effective treatment option for the short-term treatment and long-term control of atopic eczema in paediatric patients and there is no evidence for systemic adverse events, immune suppression or alterations in the vaccine response, after short- term or prolonged treatment.
Journal ArticleDOI

The validity and reliability of the occupational contact dermatitis disease severity index

TL;DR: The occupational contact dermatitis disease severity index (ODDI) was designed to assess the severity and importantly the functional disability caused by occupational Contact dermatitis of the hands in patients attending the occupational dermatology clinic.
Journal ArticleDOI

Reliéva, a Mahonia aquifolium extract for the treatment of adult patients with atopic dermatitis.

TL;DR: Reliéva cream appears to be a safe and effective treatment for adult patients with atopic dermatitis (eczema) in an open-label trial.
References
More filters
Book

The design and analysis of clinical experiments

TL;DR: The Parallel Groups Design as mentioned in this paper is a special case of the Parallel Groups Study, and it is used to control for prognostic variables in linear regression analysis of linear regressions of linear models.
Journal Article

Diagnostic features of atopic dermatitis

Journal ArticleDOI

Severe psoriasis--oral therapy with a new retinoid.

T. Fredriksson, +1 more
- 01 Jan 1978 - 
TL;DR: Ro 10--9359 proved to be an extremely potent antipsoriatic drug and a more than 90% reduction of psoriatic lesions could be seen in 10 patients out of 20 after 4-8 weeks of treatment.
Journal ArticleDOI

Large sample standard errors of kappa and weighted kappa.

TL;DR: The statistics kappa and weighted kappa (Cohen, 1960) were introduced to provide coefficients of agreement between two raters for nominal scales as discussed by the authors, and they were used to provide a measure of the relative seriousness of the different possible disagreements.
Related Papers (5)