Journal ArticleDOI
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis
Jon M. Hanifin,Thurston M,Thurston M,Omoto M,Omoto M,R. Cherill,R. Cherill,Susan J. Tofte,Graeber M,Graeber M +9 more
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TLDR
In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.Abstract:
:Objective– To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. Design: Training of evaluators, application, and assessment over 2 consecutive days. Setting– An academic center. Patients– Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients ≥8 years) and cohort 2 (10 patients <8 years). Interventions– None. Main outcome measure– The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. Results– Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. Conclusions– This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.read more
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Defining Digital Measurement of Scratching During Sleep, or “Nocturnal Scratch”: a Systematic Review of the Literature (Preprint)
TL;DR: In this paper , a systematic literature review of English-language studies published between January 1996 and March 2022 was performed to compare different technologies for assessing scratching during sleep (nocturnal scratch) in patients with inflammatory skin conditions.
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TL;DR: In this paper , the association of the filaggrin (FLG) gene with atopic dermatitis (AD) in Caucasians from Central Russia was studied in the sample of 700 patients and 612 controls.
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Efficacy of dupilumab in moderate and severe atopic dermatitis
TL;DR: In this article , the authors assessed dupilumab response by baseline AD severity in 1719 patients aged ≥12 years with moderate-to-severe AD from five randomized, double-blind, placebo-controlled trials.
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Wahrnehmung der Corona‐Pandemie durch Neurodermitispatienten – Ergebnisse aus dem Neurodermitisregister TREATgermany
TL;DR: TREATgermany as discussed by the authors , a registry for patients with moderate to severe atopic dermatitis (AD), established an additional questionnaire in spring 2020 to investigate effects of the coronavirus pandemic on the daily life of patients with AD.
Journal ArticleDOI
Establishment and Utility of SwedAD: A Nationwide Swedish Registry for Patients with Atopic Dermatitis Receiving Systemic Pharmacotherapy.
Mikael Alsterholm,Axel Svedbom,C. D. Anderson,Lena Ivert,Anna Josefson,L.B. von Kobyletzki,Magnus Lindberg,Lena Lundeberg,Eva Nylander,Alexander Shayesteh,Gunnthorunn Sigurdardottir,Andreas Sonesson,Åke Svensson,Marie Virtanen,Carl-Fredrik Wahlgren,Maria Bradley,Emma Kristin Johansson +16 more
TL;DR: SwedAD as mentioned in this paper is a Swedish registry for patients with atopic dermatitis receiving systemic pharmacotherapy, which was launched on 1 September 2019 and was used to provide a user-friendly registry to the benefit of patients.
References
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Severity Scoring of Atopic Dermatitis: The SCORAD Index
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