Journal ArticleDOI
The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis
Jon M. Hanifin,Thurston M,Thurston M,Omoto M,Omoto M,R. Cherill,R. Cherill,Susan J. Tofte,Graeber M,Graeber M +9 more
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TLDR
In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.Abstract:
:Objective– To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. Design: Training of evaluators, application, and assessment over 2 consecutive days. Setting– An academic center. Patients– Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients ≥8 years) and cohort 2 (10 patients <8 years). Interventions– None. Main outcome measure– The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. Results– Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. Conclusions– This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.read more
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Warm, humid, and high sun exposure climates are associated with poorly controlled eczema: PEER (Pediatric Eczema Elective Registry) cohort, 2004-2012.
TL;DR: Multivariate logistic regression modeling adjusting for gender, race, income, and topical medication use demonstrated that higher temperature and increased sun exposure were associated with poorly controlled eczema.
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MAS063DP is effective monotherapy for mild to moderate atopic dermatitis in infants and children: a multicenter, randomized, vehicle-controlled study.
Mark Boguniewicz,Joshua A. Zeichner,Lawrence F. Eichenfield,Adelaide A. Hebert,Michael Jarratt,Anne W. Lucky,Amy S. Paller +6 more
TL;DR: MAS063DP cream is effective and safe as monotherapy for the treatment of symptoms of mild to moderate atopic dermatitis in infants and children.
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Improvement of atopic dermatitis skin symptoms by Vitreoscilla filiformis bacterial extract.
Audrey Gueniche,Anca Hennino,Catherine Goujon,Karima Dahel,Philippe Bastien,Richard Martin,Roland Jourdain,Lionel Breton +7 more
TL;DR: Treatment with the ointment containing 5% V.f. extract significantly improved the AD skin symptoms and results suggest that V. f.
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Measuring atopic eczema severity visually: which variables are most important to patients?
TL;DR: From the patient's perspective, the measurement of 3 clinical signs-excoriations, erythema, and edema/papulation-provides as much information about current atopic eczema severity as more complex scoring systems that measure multiple clinical signs and disease extent.
Journal ArticleDOI
The value of SCORAD and beyond. Towards a standardized evaluation of severity
Carlo Gelmetti,C. Colonna +1 more
TL;DR: The clinical scoring systems of atopic dermatitis were analysed and compared, and some biological parameters that can correlate with the clinical score were also reviewed.
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Severity Scoring of Atopic Dermatitis: The SCORAD Index
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