scispace - formally typeset
Journal ArticleDOI

The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis

Reads0
Chats0
TLDR
In this paper, the reliability of the EASI scoring system was evaluated by assessing inter-and intra-observer consistency, and the results indicated that the evaluators assessed the patients consistently across both study days.
Abstract
:Objective– To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency. Design: Training of evaluators, application, and assessment over 2 consecutive days. Setting– An academic center. Patients– Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients ≥8 years) and cohort 2 (10 patients <8 years). Interventions– None. Main outcome measure– The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed. Results– Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days. Conclusions– This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.

read more

Citations
More filters
Journal ArticleDOI

Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life.

TL;DR: The results suggest that although the stratum corneum of infants may appear intact shortly after birth, the way it stores and transports water becomes adult-like only after the first year of life.
Journal ArticleDOI

Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents.

TL;DR: Pimecrolimus cream 1% appears to be a safe and effective alternative to currently used therapies for atopic dermatitis (AD) in children and adults, allergic contact dermatitis, and chronic contact irritant hand dermatitis in adults as discussed by the authors.
Journal ArticleDOI

Skin colonization by Staphylococcus aureus in patients with eczema and atopic dermatitis and relevant combined topical therapy: a double-blind multicentre randomized controlled trial.

TL;DR: It has been determined that bacterial colonization is an important factor aggravating skin lesions in patients with eczema and atopic dermatitis and treated with antibiotics.
Journal ArticleDOI

Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?

TL;DR: This review will focus on the mediators of chronic pruritus mainly associated with atopic dermatitis (atopic itch), as well as numerous different therapeutic options.
Journal ArticleDOI

Toward a new generation of smart skins

TL;DR: Greater collaboration between engineers, biologists, informaticians and clinicians will be required for smart skins to realize their full potential and attain wide adoption in a diverse range of real-world settings.
References
More filters
Book

The design and analysis of clinical experiments

TL;DR: The Parallel Groups Design as mentioned in this paper is a special case of the Parallel Groups Study, and it is used to control for prognostic variables in linear regression analysis of linear regressions of linear models.
Journal Article

Diagnostic features of atopic dermatitis

Journal ArticleDOI

Severe psoriasis--oral therapy with a new retinoid.

T. Fredriksson, +1 more
- 01 Jan 1978 - 
TL;DR: Ro 10--9359 proved to be an extremely potent antipsoriatic drug and a more than 90% reduction of psoriatic lesions could be seen in 10 patients out of 20 after 4-8 weeks of treatment.
Journal ArticleDOI

Large sample standard errors of kappa and weighted kappa.

TL;DR: The statistics kappa and weighted kappa (Cohen, 1960) were introduced to provide coefficients of agreement between two raters for nominal scales as discussed by the authors, and they were used to provide a measure of the relative seriousness of the different possible disagreements.
Related Papers (5)