Journal ArticleDOI
The neurobiology of learning and memory
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TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.Abstract:
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.read more
Citations
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Journal ArticleDOI
Temporal Discrimination Learning in Abstinent Chronic Alcoholics
TL;DR: It was speculated that cerebellar cortical atrophy caused by years of alcohol abuse resulted in the peak latency alteration and that atrophy extending into deep Cerebellar nuclei caused the overall impairment in conditioned response acquisition.
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Conditional motor learning in the nonspatial domain: effects of errorless learning and the contribution of the fornix to one-trial learning.
TL;DR: It is found that significant 1-trial learning of conditional motor associations between the nonspatial features of visual stimuli and nonspatially differentiated responses also depended on the fornix, and removal of the hippocampus, subiculum, and subjacent parahippocampal cortex had no effect.
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Changes of synapsin I messenger RNA expression during rat brain development
Uwe-Martin Zurmöhle,Jochen Herms,Reimar Schlingensiepen,Karl-Hermann Schlingensiepen,Wolfgang Brysch +4 more
TL;DR: The persistence of synapsin I in some adult rat brain regions indicates that it plays a part in synapse formation during plastic adaption in neuronal connectivities.
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The Contribution of Brainstem and Cerebellar Pathways to Auditory Recognition.
TL;DR: It is reasoned that plasticity in the cerebellar pathways underpins implicit learning of spectrotemporal information necessary for sound and speech recognition, and could support a range of auditory processing functions such as streaming, habituation, and the integration of auditory feature information such as pitch.
Journal ArticleDOI
Evolutionary Perspectives on Emotion: Making Sense of What We Feel
TL;DR: In this paper, an evolution-based approach to emotions, in hand with an understanding of developmental processes, can enrich our therapies and point to new ways of working directly with emotions.
References
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Journal ArticleDOI
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.
Timothy V. P. Bliss,T. Lømo +1 more
TL;DR: The after‐effects of repetitive stimulation of the perforant path fibres to the dentate area of the hippocampal formation have been examined with extracellular micro‐electrodes in rabbits anaesthetized with urethane.
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A Theory of Cerebellar Cortex
TL;DR: A detailed theory of cerebellar cortex is proposed whose consequence is that the cerebellum learns to perform motor skills and two forms of input—output relation are described, both consistent with the cortical theory.
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A Theory of Cerebellar Function
TL;DR: It is demonstrated that, in order for the learning process to be stable, pattern storage must be accomplished principally by weakening synaptic weights rather than by strengthening them.
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Habituation: A model phenomenon for the study of neuronal substrates of behavior.
TL;DR: An apparatus for cleaning and sterilizing objects, such as pharmaceutical caps, plugs and the like, includes an autoclave chamber and a cleaning device having a cleaning drum mounted for a free rotation on a frame.
Journal ArticleDOI
Hippocampus, space, and memory
TL;DR: It is proposed that the hippocampus is selectively involved in behaviors that require working memory, irrespective of the type of material (spatial or nonspatial) that is to be processed by that memory.