Journal ArticleDOI
The neurobiology of learning and memory
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TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.Abstract:
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.read more
Citations
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Journal ArticleDOI
Eyeblink classical conditioning in H.M. : delay and trace paradigms
TL;DR: Results suggest that humans can condition in the 400-ms delay and 900-ms trace EBCC paradigms with the hippocampus radically excised.
Book ChapterDOI
Multiple systems of perceptual category learning: theory and cognitive tests
TL;DR: This theory of multiple systems in category learning, called COVIS, is described in detail and a variety of cognitive behavioral and cognitive neuroscience experiments are reviewed that test some parameter-free a priori predictions made by COVIS.
Patent
Process and apparatus for the automatic detection and extraction of features in images and displays
TL;DR: In this paper, a pattern recognition process and apparatus automatically extracts features in displays, images, and complex signals, which can be used within a control system to automatically guide an object, such as a vehicle or airplane, along a desired course; or within a signal processing system to provide a display of the features in a way that aids in the interpretation of such features.
Journal ArticleDOI
Correlations between active zone ultrastructure and synaptic function studied with freeze-fracture of physiologically identified neuromuscular junctions.
J. W. Propst,Chien-Ping Ko +1 more
TL;DR: Frog neuromuscular junctions were studied with a new technique combining electrophysiology, light microscopy, and freeze- fracture of identified single muscle fibers to suggest that active zone size and spacing are better indicators of transmitter release than is endplate size and that the active zone may play an important role in regulating synaptic efficacy at the neuromUScular junction.
Neural Representation of Conceptual Knowledge.
TL;DR: There is now good reason to reject both extreme views, but a compact encoding that derives from the punctate model appears to fit well with all the facts.
References
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Journal ArticleDOI
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.
Timothy V. P. Bliss,T. Lømo +1 more
TL;DR: The after‐effects of repetitive stimulation of the perforant path fibres to the dentate area of the hippocampal formation have been examined with extracellular micro‐electrodes in rabbits anaesthetized with urethane.
Journal ArticleDOI
A Theory of Cerebellar Cortex
TL;DR: A detailed theory of cerebellar cortex is proposed whose consequence is that the cerebellum learns to perform motor skills and two forms of input—output relation are described, both consistent with the cortical theory.
Journal ArticleDOI
A Theory of Cerebellar Function
TL;DR: It is demonstrated that, in order for the learning process to be stable, pattern storage must be accomplished principally by weakening synaptic weights rather than by strengthening them.
Journal ArticleDOI
Habituation: A model phenomenon for the study of neuronal substrates of behavior.
TL;DR: An apparatus for cleaning and sterilizing objects, such as pharmaceutical caps, plugs and the like, includes an autoclave chamber and a cleaning device having a cleaning drum mounted for a free rotation on a frame.
Journal ArticleDOI
Hippocampus, space, and memory
TL;DR: It is proposed that the hippocampus is selectively involved in behaviors that require working memory, irrespective of the type of material (spatial or nonspatial) that is to be processed by that memory.