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Journal ArticleDOI

The neurobiology of learning and memory

Richard F. Thompson
- 29 Aug 1986 - 
- Vol. 233, Iss: 4767, pp 941-947
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TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.
Abstract
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.

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Citations
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Q: Is the cerebellum an adaptive combiner of motor and mental/motor activities? A: Yes, maybe, certainly not, who can say?

TL;DR: In this article, a synthesis of human cerebellar functional imaging and ablation in motor learning is presented as a working hypothesis on how the cerebellum might adapt, learn, and coordinate movement.
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A single identified interneuron gates tail-shock induced inhibition in the siphon withdrawal reflex of Aplysia

TL;DR: It is reported that functional removal of a single inhibitory interneuron, L16, can eliminate most, if not all, of the inhibition in the siphon withdrawal reflex circuit produced by tail shock, and this results support the idea that behaviorally relevant neural modulation can be gated by a small number of neurons.
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Bilateral lesions in the cerebellar interpositus-dentate region impair taste aversion learning in rats

TL;DR: In this article, lesions in the interpositus-dentate region of the cerebellum have been found to impair taste aversion learning in rats, but have no effect on long-term TAL.
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Repression: The Evolution of a Psychoanalytic Concept from the 1890's to the 1990's:

TL;DR: A summary of Freud's concept of repression, including modifications of the concept from 1894 to 1932, is presented, outlining how the different models might apply to the different types of repression.
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Rhodiola rosea L. Improves Learning and Memory Function: Preclinical Evidence and Possible Mechanisms.

TL;DR: A systematic review and meta-analysis for preclinical studies suggested that R. rosea L. can improve learning and memory function in animal models.
References
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Journal ArticleDOI

Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.

TL;DR: The after‐effects of repetitive stimulation of the perforant path fibres to the dentate area of the hippocampal formation have been examined with extracellular micro‐electrodes in rabbits anaesthetized with urethane.
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A Theory of Cerebellar Cortex

TL;DR: A detailed theory of cerebellar cortex is proposed whose consequence is that the cerebellum learns to perform motor skills and two forms of input—output relation are described, both consistent with the cortical theory.
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A Theory of Cerebellar Function

TL;DR: It is demonstrated that, in order for the learning process to be stable, pattern storage must be accomplished principally by weakening synaptic weights rather than by strengthening them.
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Habituation: A model phenomenon for the study of neuronal substrates of behavior.

TL;DR: An apparatus for cleaning and sterilizing objects, such as pharmaceutical caps, plugs and the like, includes an autoclave chamber and a cleaning device having a cleaning drum mounted for a free rotation on a frame.
Journal ArticleDOI

Hippocampus, space, and memory

TL;DR: It is proposed that the hippocampus is selectively involved in behaviors that require working memory, irrespective of the type of material (spatial or nonspatial) that is to be processed by that memory.
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