Journal ArticleDOI
The neurobiology of learning and memory
Reads0
Chats0
TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.Abstract:
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.read more
Citations
More filters
Journal ArticleDOI
A synaptic model of memory: long-term potentiation in the hippocampus
TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
Journal ArticleDOI
Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
TL;DR: The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
Journal ArticleDOI
A systematic method for clinical description and classification of personality variants: A proposal.
TL;DR: In this article, a method for clinical description and classification of both normal and abnormal personality variants is proposed based on a general biosocial theory of personality, and three dimensions of personality are defined in terms of the basic stimulus-response characteristics of novelty seeking, harm avoidance and reward dependence.
Journal ArticleDOI
The medial temporal lobe memory system
TL;DR: The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory, but the role of this system is only temporary, as time passes after learning, memory stored in neoc cortex gradually becomes independent of medialporal lobe structures.
Journal ArticleDOI
Neurogenetic adaptive mechanisms in alcoholism
TL;DR: In this paper, three dimensions of personality have been described that may reflect individual differences in brain systems modulating the activation, maintenance, and inhibition of behavioral responses to the effects of alcohol and other environmental stimuli.
References
More filters
Journal ArticleDOI
The Neural Basis of Language
TL;DR: Until the middle of the 1960s, the understanding of the anatomical basis of language in humans had grown on the strength of a handful of methods, the oldest of which was the neuropathological study of focal cerebral lesions in patients with aphasia.
Journal ArticleDOI
Associative long-term potentiation in hippocampal slices.
TL;DR: This form of long-term synaptic potentiation (LTP), known as associative LTP, was shown in some cases to last hours without decrement and could not be accounted for by any of several measured postsynaptic passive membrane properties.
Journal ArticleDOI
An instruction-selection theory of learning in the cerebellar cortex.
TL;DR: It is now generally recognized that the cerebellum has a computer-like function in regard to a wide range of performances generated in the central nervous system.
Journal ArticleDOI
Hormonal Influences on Memory
TL;DR: Hobos as endogenous MODULATORS of memory as well as central EFFECTS of HORMONES are studied.
Journal ArticleDOI
Reversal of structural and functional effects of long-term visual deprivation in cats
Kao Liang Chow,David L. Stewart +1 more
TL;DR: In this paper, the authors found that the receptive fields of lateral geniculate (LGN) and striate cortex cells were essentially normal except for cortical ocular dominance patterns.