Journal ArticleDOI
The neurobiology of learning and memory
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TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.Abstract:
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.read more
Citations
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A synaptic model of memory: long-term potentiation in the hippocampus
TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
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Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
TL;DR: The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
Journal ArticleDOI
A systematic method for clinical description and classification of personality variants: A proposal.
TL;DR: In this article, a method for clinical description and classification of both normal and abnormal personality variants is proposed based on a general biosocial theory of personality, and three dimensions of personality are defined in terms of the basic stimulus-response characteristics of novelty seeking, harm avoidance and reward dependence.
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The medial temporal lobe memory system
TL;DR: The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory, but the role of this system is only temporary, as time passes after learning, memory stored in neoc cortex gradually becomes independent of medialporal lobe structures.
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Neurogenetic adaptive mechanisms in alcoholism
TL;DR: In this paper, three dimensions of personality have been described that may reflect individual differences in brain systems modulating the activation, maintenance, and inhibition of behavioral responses to the effects of alcohol and other environmental stimuli.
References
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Journal ArticleDOI
Crayfish escape behavior and central synapses. II. Physiological mechanisms underlying behavioral habituation.
TL;DR: It was shown that the excitation of some tactile interneurons by tactile afferents antifacilitates extensively at low repetition rates, and it is not clear that this is the only phenomenon responsible for generating lability in the behavior.
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A review of electrical stimulation of the brain in context of learning and retention.
TL;DR: A selective review of the literature on the effect of electrical stimulation of the brain on learning and memory processes is presented, and tentative suggestions are advanced relating these effects to processes associated with storage and retrieval of information.
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Two forms of human amnesia: an analysis of forgetting
TL;DR: An analysis of forgetting was applied to patients with Korsakoff's syndrome, patients receiving bilateral electroconvulsive therapy (ECT), and case N. A. who has chronic amnesia for verbal material, supporting the hypothesis that these amnesias are distinct syndromes of memory dysfunction.
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Effect of kainic acid lesions of the cerebellar interpositus nucleus on eyelid conditioning in the rabbit.
TL;DR: It is demonstrated that kainic acid lesions of the dorsal interpositus nucleus are sufficient for selectively abolish or prevent a classically conditioned nictitating membrane/eyelid response in rabbits.
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Classical conditioning of the rabbit eyelid response with a mossy-fiber stimulation CS: I. Pontine nuclei and middle cerebellar peduncle stimulation.
TL;DR: The nictitating membrane/eyelid responses of 18 rabbits were classically conditioned using cerebellar mossy-fiber stimulation as a conditioned stimulus (CS) and air puff as an unconditioned stimulus (US).