Journal ArticleDOI
The neurobiology of learning and memory
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TLDR
Probably applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.Abstract:
Study of the neurobiology of learning and memory is in a most exciting phase. Behavioral studies in animals are characterizing the categories and properties of learning and memory; essential memory trace circuits in the brain are being defined and localized in mammalian models; work on human memory and the brain is identifying neuronal systems involved in memory; the neuronal, neurochemical, molecular, and biophysical substrates of memory are beginning to be understood in both invertebrate and vertebrate systems; and theoretical and mathematical analysis of basic associative learning and of neuronal networks in proceeding apace. Likely applications of this new understanding of the neural bases of learning and memory range from education to the treatment of learning disabilities to the design of new artificial intelligence systems.read more
Citations
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A synaptic model of memory: long-term potentiation in the hippocampus
TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
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Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.
TL;DR: The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
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A systematic method for clinical description and classification of personality variants: A proposal.
TL;DR: In this article, a method for clinical description and classification of both normal and abnormal personality variants is proposed based on a general biosocial theory of personality, and three dimensions of personality are defined in terms of the basic stimulus-response characteristics of novelty seeking, harm avoidance and reward dependence.
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The medial temporal lobe memory system
TL;DR: The medial temporal lobe memory system is needed to bind together the distributed storage sites in neocortex that represent a whole memory, but the role of this system is only temporary, as time passes after learning, memory stored in neoc cortex gradually becomes independent of medialporal lobe structures.
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Neurogenetic adaptive mechanisms in alcoholism
TL;DR: In this paper, three dimensions of personality have been described that may reflect individual differences in brain systems modulating the activation, maintenance, and inhibition of behavioral responses to the effects of alcohol and other environmental stimuli.
References
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Journal ArticleDOI
Entorhinal and septal inputs differentially control sensory-evoked responses in the rat dentate gyrus
TL;DR: The findings indicate that the entorhinal and septal projections to the dentate granule cells are activated differentially by sensory stimuli as a function of their acquired behavioral significance to the animal.
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A common presynaptic locus for the synaptic changes underlying short-term habituation and sensitization of the gill-withdrawal reflex in Aplysia.
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Extrinsic modulation of crayfish escape behaviour.
TL;DR: Extrinsic systems were shown to control the excitability of the neurones which mediate tail-flip escape in the crayfish, and inhibition may serve to shift the control of escape behaviour to more flexible 'voluntary' ones which can produce responses at times most opportune for successful escape.
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Physiology and psychiatry.
TL;DR: Today the neuro-anatomist and physiologist are still crudely deciphering the architecture and operation of the organ of mind; the psychologist and psychiatrist are concerned with nuances in the overtones it plays.
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Fractured cutaneous projections to the granule cell layer of the posterior cerebellar hemisphere of the domestic cat.
TL;DR: The Organization of cutaneous projections to eortibellar hemispheric cortex in cats is reexamined by using micromapping methods.