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Charles D. Johnson

Researcher at Texas A&M University

Publications -  28
Citations -  5852

Charles D. Johnson is an academic researcher from Texas A&M University. The author has contributed to research in topics: Deep sequencing & Transcriptome. The author has an hindex of 19, co-authored 26 publications receiving 5483 citations. Previous affiliations of Charles D. Johnson include Texas AgriLife Research & University of Louisville.

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The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

Leming Shi, +136 more
- 01 Sep 2006 - 
TL;DR: This study describes the experimental design and probe mapping efforts behind the MicroArray Quality Control project and shows intraplatform consistency across test sites as well as a high level of interplatform concordance in terms of genes identified as differentially expressed.
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The let-7 MicroRNA represses cell proliferation pathways in human cells

TL;DR: This work reveals the let-7 microRNA to be a master regulator of cell proliferation pathways and shows that multiple genes involved in cell cycle and cell division functions are also directly or indirectly repressed byLet-7.
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A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

Zhenqiang Su, +164 more
- 01 Sep 2014 - 
TL;DR: The complete SEQC data sets, comprising >100 billion reads, provide unique resources for evaluating RNA-seq analyses for clinical and regulatory settings, and measurement performance depends on the platform and data analysis pipeline, and variation is large for transcript-level profiling.
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The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

Leming Shi, +201 more
- 01 Aug 2010 - 
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.
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Genome-Scale MicroRNA and Small Interfering RNA Screens Identify Small RNA Modulators of TRAIL-Induced Apoptosis Pathway

TL;DR: Libraries of synthetic small interfering RNA (siRNA) and microRNAs (miRNA) were used to probe the TRAIL pathway and revealed novel genes, including CDK4, the only member of the cyclin-dependent kinase gene family that bore a unique function in apoptotic signal transduction.