H
Hiroaki Shimokawa
Researcher at Tohoku University
Publications - 976
Citations - 56856
Hiroaki Shimokawa is an academic researcher from Tohoku University. The author has contributed to research in topics: Heart failure & Endothelium. The author has an hindex of 111, co-authored 949 publications receiving 48822 citations. Previous affiliations of Hiroaki Shimokawa include University of Nebraska Medical Center & Nagoya University.
Papers
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Journal Article
Long-Term Inhibition of Rho-Kinase Suppresses Cardiac Allograft Vasculopathy in Mice : Possible Involvement of Macrophage Migration Inhibitory Factor (MIF)
Tsuyoshi Hattori,Hiroaki Shimokawa,Midoriko Higashi,Junko Hiroki,Yasushi Mukai,Akira Takeshita +5 more
Journal ArticleDOI
Insights to advance our management of myocardial ischemia: From obstructive epicardial disease to functional coronary alterations
C. Noel Bairey Merz,John F. Beltrame,Colin Berry,Colin Berry,William E. Boden,Paolo G. Camici,Filippo Crea,Judith S. Hochman,Juan Carlos Kaski,Patrick T. O'Gara,Peter Ong,Carl J. Pepine,Hiroaki Shimokawa,Udo Sechtem,Gregg W. Stone +14 more
TL;DR: In this article, the authors address strategies to enhance our clinical understanding of INOCA with an emphasis on the management of coronary vasomotor disorders, distinguishing different presentations of angina due to vasospasm and abnormal microvascular vasodilatation, developing invasive/non-invasive testing and treatment protocols, integrating diagnostic protocols into cardiologists' workflow and trials to inform guideline development.
Patent
Pulmonary hypertension preventative or therapeutic agent containing crude drug
Hiroaki Shimokawa,Hidetoshi Tokuyama,Hirofumi Ueda,Aoki Jyunken,Takayuki Doi,Kuniyuki Kano,Kimio Satoh,Ryo Kurosawa +7 more
TL;DR: In this paper, the authors proposed a preventive or therapeutic agent for pulmonary hypertension containing emetine or a salt thereof, which has not been known for a therapeutic effect on pulmonary hypertension heretofore.
Journal ArticleDOI
Localized dissection of the sinus of Valsalva mimicking spontaneous coronary artery dissection
TL;DR: A 56-year-old man, suspected of having ST-segment elevation myocardial infarction due to spontaneous coronary artery dissection, underwent emergency percutaneous coronary intervention as mentioned in this paper .
Book ChapterDOI
Epidemiology of Vasospastic Angina
Jun Takahashi,Hiroaki Shimokawa +1 more
TL;DR: In this paper, the authors reviewed the epidemiological data regarding VSA from a broad set of perspectives, including demographic characteristics, incidence and prognosis, risk and precipitating factors, and other recent clinical topics.