H
Hiroaki Shimokawa
Researcher at Tohoku University
Publications - 976
Citations - 56856
Hiroaki Shimokawa is an academic researcher from Tohoku University. The author has contributed to research in topics: Heart failure & Endothelium. The author has an hindex of 111, co-authored 949 publications receiving 48822 citations. Previous affiliations of Hiroaki Shimokawa include University of Nebraska Medical Center & Nagoya University.
Papers
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Journal ArticleDOI
Vanadate causes synthesis of endothelium-derived NO via pertussis toxin- sensitive G protein in pigs
Ryuichi Nakaike,Hiroaki Shimokawa,M. K. Owada,O. Tokunaga,Hiroshi Yasutake,T. Kishimoto,C. Imada,T. Shiraishi,Kensuke Egashira,Akira Takeshita +9 more
TL;DR: Results indicate that in porcine blood vessels, vanadate causes a synthesis of endothelium-derived NO for which endothelial tyrosine kinases and pertussis toxin-sensitive G protein are considered to be closely involved.
Journal ArticleDOI
Prognostic impacts of dynamic cardiac structural changes in heart failure patients with preserved left ventricular ejection fraction.
Shinsuke Yamanaka,Yasuhiko Sakata,Kotaro Nochioka,Masanobu Miura,Shintaro Kasahara,Masayuki Sato,Hajime Aoyanagi,Takahide Fujihashi,Hideka Hayashi,Takashi Shiroto,Koichiro Sugimura,Jun Takahashi,Satoshi Miyata,Hiroaki Shimokawa,Chart Investigators +14 more
TL;DR: This work aimed to examine temporal changes in left ventricular structures and their prognostic impacts in patients with heart failure (HF) and preserved ejection fraction (HFpEF) and to assess the impact of these changes on clinical practice and disease progression.
Patent
Stent adhered and coated with medicine and its production
TL;DR: In this article, the authors present a method to securely adhere a medicine having effect of preventing and treating the hypertrophy of artery intima and to gradually release this medicine into the body fluid by subjecting a stent to adhering and coating of the medicine by using a bioadaptable polymer and/or biodegradable polymer.
Journal Article
Visceral larva migrans by Toxocara cati.
Journal ArticleDOI
Viral genome search in myocardium of patients with fulminant myocarditis
Giacomo Veronese,Enrico Ammirati,Michela Brambatti,Marco Merlo,Manlio Cipriani,Luciano Potena,Paola Sormani,Tatsuo Aoki,Koichiro Sugimura,Akinori Sawamura,Takahiro Okumura,Sean Pinney,Kimberly N. Hong,Palak Shah,Oscar Ö. Braun,Caroline M. Van De Heyning,Santiago Montero,Santiago Montero,Duccio Petrella,Florent Huang,Matthieu Schmidt,Claudia Raineri,Anuradha Lala,Marisa Varrenti,Alberto Foà,Ornella Leone,Piero Gentile,Jessica Artico,Valentina Agostini,Rajiv Patel,Andrea Garascia,Emeline M. Van Craenenbroeck,Kaoru Hirose,Akihiro Isotani,Toyoaki Murohara,Yoh Arita,Alessandro Sionis,Enrico Fabris,Sherin Hashem,Victor Garcia-Hernando,Fabrizio Oliva,Barry H. Greenberg,Hiroaki Shimokawa,Gianfranco Sinagra,Eric Adler,Maria Frigerio,Paolo G. Camici +46 more
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the immune system’s response to heart attack and stroke.