H
Hiroaki Shimokawa
Researcher at Tohoku University
Publications - 976
Citations - 56856
Hiroaki Shimokawa is an academic researcher from Tohoku University. The author has contributed to research in topics: Heart failure & Endothelium. The author has an hindex of 111, co-authored 949 publications receiving 48822 citations. Previous affiliations of Hiroaki Shimokawa include University of Nebraska Medical Center & Nagoya University.
Papers
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Journal ArticleDOI
Prognostic Significance of PR Interval Prolongation in Adult Patients With Total Correction of Tetralogy of Fallot.
Yoshitaka Kimura,Koji Fukuda,Makoto Nakano,Yuhi Hasebe,Kyoshiro Fukasawa,Takahiko Chiba,Keita Miki,Shunsuke Tatebe,Satoshi Miyata,Hideki Ota,Masato Kimura,Osamu Adachi,Yoshikatsu Saiki,Hiroaki Shimokawa +13 more
TL;DR: It is indicated that progressive atrioventricular conduction disturbance is correlated with right ventricular enlargement and could be a useful predictor for increased risk of lethal ventricular arrhythmias in patients with repaired tetralogy of Fallot.
Journal ArticleDOI
Significance of Defective Endothelial Signal Transduction in Impaired Endothelium-Dependent Relaxation in Atherosclerosis
TL;DR: The dysfunction of pertussis toxin-sensitive G protein (Gi protein) may contribute to the impairment of the endothelium-dependent relaxations in atherosclerosis.
Book ChapterDOI
Pathophysiology of Coronary Microvascular Dysfunction
Shigeo Godo,Hiroaki Shimokawa +1 more
TL;DR: In this article, the authors summarized the latest knowledge on the pathophysiology of CMD with a special reference to endothelial modulation of vascular tone mediated by H2O2/EDH factor and coronary microvascular spasm, in addition to discussing clinical implications of and therapeutic approaches to CMD in cardiovascular disease.
Journal ArticleDOI
Correlations Between Recruitable Coronary Collateral Flow Velocities, Distal Occlusion Pressure, and Electrocardiographic Changes in Patients Undergoing Angioplasty
TL;DR: The goal of this study was to correlate the magnitudes and waveform characteristics of recruitable coronary collateral flow velocity measured with Doppler guidewire with other hemodynamic and functional indexes of collateral circulation in patients during angioplasty to find functionally significant coronary collaterals showed greater velocity signals and systolic predominance in flow pattern.
Journal ArticleDOI
Multiple sclerosis lesion in the medulla oblongata in a patient with takotsubo cardiomyopathy
Katsuya Kozu,Hideaki Suzuki,Shuhei Nishiyama,Nobuhiro Yaoita,Saori Yamamoto,Shunsuke Tatebe,Masanobu Miura,Tatsuo Aoki,Kiyotaka Hao,Yasuharu Matsumoto,Koichiro Sugimura,Masashi Aoki,Hiroaki Shimokawa +12 more